Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)

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MLC1; MLC1F; MLC3F; Myosin light chain 1/3, skeletal muscle isoform; Myosin light chain A1/A2

Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)

In vertebrate striated muscle, myosin is composed of 2 heavy chains of about 200,000 daltons each and 4 light chains of about 20,000 daltons each. The light chains are of 2 distinct types: the phosphorylatable, regulatory, or MLC2 type, and the nonphosphorylatable, alkali, or MLC1 and MLC3 types (MYL1 according to the HGM symbols). The previously uncharacterized zebrafish alkali-like myosin light chain gene (myl1) was found to be expressed exclusively in cells in the fast-twitch pathway initiated at an early stage of fast fibre differentiation. Myl1 was expressed earlier, and in a more fibre type restricted manner, than any of the previously described and frequently used fast myosin light and heavy chain and troponin muscle markers mylz2, mylz3, tnni2, tnnt3a, fMyHC1.3.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB105Hu01Recombinant Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling.
AntibodiesPAB105Hu01Polyclonal Antibody to Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
MAB105Hu22Monoclonal Antibody to Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEB105HuELISA Kit for Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)CLIA Kit Customized Service Offer
n/aELISA Kit for Myosin Light Chain 1, Alkali, Fast Skeletal (MYL1)ELISA Kit Customized Service Offer
  1. "The complete nucleotide sequences of cDNA clones coding for human myosin light chains 1 and 3."Nucleic Acids Res. 15:4989-4989(1987) [PubMed] [Europe PMC] [Abstract]
  2. "Alkali myosin light chains in man are encoded by a multigene family that includes the adult skeletal muscle, the embryonic or atrial, and nonsarcomeric isoforms."Gene 66:135-146(1988) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Identification of the functional promoter regions in the human gene encoding the myosin alkali light chains MLC1 and MLC3 of fast skeletal muscle."J. Biol. Chem. 264:16109-16117(1989) [PubMed] [Europe PMC] [Abstract]