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Contactin 1 (CNTN1)

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F3; Glycoprotein gP135; Neural cell surface protein F3

Contactin 1 (CNTN1)
CCC B201
HGNC 2171
MGI 105980
PubMed 16510572
RGD 621300
UniProt Q12860
Wiki CNTN1

Contactin 1, also known as CNTN1, is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Chick contactin (also known as F11 in the chick and F3 in the mouse) is a neuronal cell adhesion molecule of the immunoglobulin superfamily that is composed of 6 C2 Ig domains and 4 fibronectin type III (FN-III) repeats. In the developing mouse cerebellum, contactin is confined to discrete neuronal subpopulations and subcompartments, for example, the granule cell axons, Golgi cells, and mossy fibers, while in contrast, stellate cells and Purkinje cell bodies and dendrites are devoid of contactin expression.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB201Hu01 Recombinant Contactin 1 (CNTN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB201Hu01 Polyclonal Antibody to Contactin 1 (CNTN1) WB; IHC; ICC; IP.
MAB201Hu22 Monoclonal Antibody to Contactin 1 (CNTN1) WB; IHC; ICC; IP.
Assay Kits SEB201Hu ELISA Kit for Contactin 1 (CNTN1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB201Hu CLIA Kit for Contactin 1 (CNTN1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB201Mu01 Recombinant Contactin 1 (CNTN1) Positive Control; Immunogen; SDS-PAGE; WB.
RPB201Mu02 Recombinant Contactin 1 (CNTN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB201Mu01 Polyclonal Antibody to Contactin 1 (CNTN1) WB; IHC; ICC; IP.
PAB201Mu02 Polyclonal Antibody to Contactin 1 (CNTN1) WB; IHC; ICC; IP.
Assay Kits SEB201Mu ELISA Kit for Contactin 1 (CNTN1) Enzyme-linked immunosorbent assay for Antigen Detection.
SCB201Mu CLIA Kit for Contactin 1 (CNTN1) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB201Ra01 Recombinant Contactin 1 (CNTN1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB201Ra01 Polyclonal Antibody to Contactin 1 (CNTN1) WB; IHC; ICC; IP.
MAB201Ra21 Monoclonal Antibody to Contactin 1 (CNTN1) WB; IHC; ICC; IP.
Assay Kits SEB201Ra ELISA Kit for Contactin 1 (CNTN1) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Identification and characterization of the human cell adhesion molecule contactin."Brain Res. Mol. Brain Res. 21:1-8(1994) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12."Genomics 21:571-582(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Isolation and characterization of a membrane glycoprotein from human brain with sequence similarities to cell adhesion proteins from chicken and mouse."Eur. J. Biochem. 197:549-554(1991) [PubMed] [Europe PMC] [Abstract]
  6. "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."J. Proteome Res. 4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
  7. "A strategy for precise and large scale identification of core fucosylated glycoproteins."Mol. Cell. Proteomics 8:913-923(2009) [PubMed] [Europe PMC] [Abstract]
  8. "The protein tyrosine phosphatases PTPRZ and PTPRG bind to distinct members of the contactin family of neural recognition molecules."Proc. Natl. Acad. Sci. U.S.A. 107:2443-2448(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Solution structures of the FN3 domain of human contactin 1."Submitted (AUG-2007) to the PDB data bank
  10. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]
  11. "Mutations in contactin-1, a neural adhesion and neuromuscular junction protein, cause a familial form of lethal congenital myopathy."Am. J. Hum. Genet. 83:714-724(2008) [PubMed] [Europe PMC] [Abstract]