Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)

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CD152; CELIAC3; CTLA4; GSE; IDDM12; Celiac Disease 3; Cytotoxic T-lymphocyte protein 4

Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)

CTLA4 is a protein that plays an important regulatory role in the immune system. In humans, the CTLA4 protein is encoded by the CTLA4 gene.CTLA4 is a member of the immunoglobulin superfamily, which is expressed on the surface of Helper T cells and transmits an inhibitory signal to T cells.

CTLA4 is similar to the T-cell costimulatory protein CD28, and both molecules bind to CD80 and CD86 on antigen-presenting cells. CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may be important to their function. T cell activation through the T cell receptor and CD28 leads to increased expression of CTLA-4, an inhibitory receptor for B7 molecules.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB230Hu01Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB230Hu01Polyclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
MAB230Hu22Monoclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEB230HuELISA Kit for Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB230Mu01Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB230Mu01Polyclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
Assay Kitsn/aCLIA Kit for Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)CLIA Kit Customized Service Offer
n/aELISA Kit for Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB230Ra01Recombinant Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB230Ra01Polyclonal Antibody to Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)CLIA Kit Customized Service Offer
n/aELISA Kit for Cytotoxic T-Lymphocyte Associated Antigen 4 (CTLA4)ELISA Kit Customized Service Offer
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