≡

Transaldolase (TALDO1)

[Edit]

TAL; TALDO; TALDOR; Transaldolase 1

Transaldolase (TALDO1)
CCC B371
HGNC 11559
MGI 1274789
PubMed 9339383
RGD 620674
UniProt P37837
Wiki Transaldolase

Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals.

The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB371Hu01 Recombinant Transaldolase (TALDO1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB371Hu01 Polyclonal Antibody to Transaldolase (TALDO1) WB; IHC; ICC; IP.
MAB371Hu22 Monoclonal Antibody to Transaldolase (TALDO1) WB; IHC; ICC; IP.
Assay Kits SEB371Hu ELISA Kit for Transaldolase (TALDO1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB371Mu01 Recombinant Transaldolase (TALDO1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB371Mu01 Polyclonal Antibody to Transaldolase (TALDO1) WB; IHC; ICC; IP.
Assay Kits SEB371Mu ELISA Kit for Transaldolase (TALDO1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB371Ra01 Recombinant Transaldolase (TALDO1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB371Ra01 Polyclonal Antibody to Transaldolase (TALDO1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Transaldolase (TALDO1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Transaldolase (TALDO1) ELISA Kit Customized Service Offer
  1. "Cloning and expression of the human gene for transaldolase. A novel highly repetitive element constitutes an integral part of the coding sequence."J. Biol. Chem. 269:2847-2851(1994) [PubMed] [Europe PMC] [Abstract]
  2. "The human transaldolase gene (TALDO1) is located on chromosome 11 at p15.4-p15.5."Genomics 45:233-238(1997) [PubMed] [Europe PMC] [Abstract]
  3. "Cloning and chromosomal localization of a paralog and a mouse homolog of the human transaldolase gene."Gene 209:13-21(1998) [PubMed] [Europe PMC] [Abstract]
  4. "Human transaldolase-associated repetitive elements are transcribed by RNA polymerase III."J. Biol. Chem. 275:7261-7272(2000) [PubMed] [Europe PMC] [Abstract]
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  10. "The three-dimensional structure of human transaldolase."FEBS Lett. 475:205-208(2000) [PubMed] [Europe PMC] [Abstract]
  11. "Transaldolase deficiency: liver cirrhosis associated with a new inborn error in the pentose phosphate pathway."Am. J. Hum. Genet. 68:1086-1092(2001) [PubMed] [Europe PMC] [Abstract]