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Citrate Synthase (CS)

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Citrate (Si)-synthase, mitochondrial

Citrate Synthase (CS)
CCC B661
HGNC 2422
MGI 88529
PubMed 9103608
RGD 620330
UniProt O75390
Wiki CS

The enzyme citrate synthase (E.C. 2.3.3.1) exists in nearly all living cells and stands as a pace-making enzyme in the first step of the Citric Acid Cycle (or Krebs Cycle). Citrate synthase is localized within eukaryotic cells in the mitochondrial matrix, but is encoded by nuclear DNA rather than mitochondrial. It is synthesized using cytoplasmic ribosomes, then transported into the mitochondrial matrix. Citrate synthase is commonly used as a quantitative enzyme marker for the presence of intact mitochondria. Citrate synthase catalyzes the condensation reaction of the two-carbon acetate residue from acetyl coenzyme A and a molecule of four-carbon oxaloacetate to form the six-carbon citrate. Oxaloacetate will be regenerated after the completion of one round of the Krebs Cycle.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB661Hu01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB661Hu01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
MAB661Hu21 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
Assay Kits SEB661Hu ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB661Mu01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
RPB661Mu02 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB661Mu01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
PAB661Mu02 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
Assay Kits SEB661Mu ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPB661Ra01 Recombinant Citrate Synthase (CS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAB661Ra01 Polyclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
MAB661Ra21 Monoclonal Antibody to Citrate Synthase (CS) WB; IHC; ICC; IP.
Assay Kits SEB661Ra ELISA Kit for Citrate Synthase (CS) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Cloning and molecular analysis of the human citrate synthase gene."Genome 41:733-738(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Cloning and tissue expression pattern analysis of the human citrate synthase cDNA."Shi Yan Sheng Wu Xue Bao 33:207-214(2000) [PubMed] [Europe PMC] [Abstract]
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