Glycocalicin (GC)

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Carbohydrate-Rich Portion of Platelet Membrane Glycoprotein Ib Alpha Polypeptide

Glycocalicin (GC)
Glycocalicin (GC) is the carbohydrate-rich portion of platelet membrane glycoprotein Ibα that can be cleaved from circulating platelets by proteases. The plasma GC level is an indicator of platelet turnover. Glycalicin has a molecular weight of 148,000 (+/- 5,000) as determined by gel electrophoresis.Glycocalicin (GC) is a proteolytic fragment of GpIb .
Glycocalicin, a major glycoprotein of the platelet glycocalyx, is obtained in soluble forms following platelet homogenization and has been purified to homogeneity. Glycalicin has a molecular weight of 148,000 (+/- 5,000) as determined by gel electrophoresis. It contains 60 grams % carbohydrate (46.6 mol %) comprising galactose, N-acetylgalactosamine, N-acetylglucosamine, and sialic acid as its principal sugars in a ratio of 2:1:1:2, but with a small amount of glucose (2.3 mol %), mannose (1.2 mol %), and fucose (1.9 mol %).

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPB710Hu01Recombinant Glycocalicin (GC)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAB710Hu01Polyclonal Antibody to Glycocalicin (GC)WB, ICC, IHC-P, IHC-F, ELISA
LAB710Hu71Biotin-Linked Polyclonal Antibody to Glycocalicin (GC)IHC;WB;ELISA
Assay KitsSEB710HuELISA Kit for Glycocalicin (GC)Enzyme-linked immunosorbent assay