Carbohydrate-Rich Portion of Platelet Membrane Glycoprotein Ib Alpha Polypeptide
Glycocalicin (GC) is the carbohydrate-rich portion of platelet membrane glycoprotein Ib alpha that can be cleaved from circulating platelets by proteases. The plasma GC level is an indicator of platelet turnover. Glycalicin has a molecular weight of 148,000 (+/- 5,000) as determined by gel electrophoresis.Glycocalicin (GC) is a proteolytic fragment of GpIb .
Glycocalicin, a major glycoprotein of the platelet glycocalyx, is obtained in soluble forms following platelet homogenization and has been purified to homogeneity. Glycalicin has a molecular weight of 148,000 (+/- 5,000) as determined by gel electrophoresis. It contains 60 grams % carbohydrate (46.6 mol %) comprising galactose, N-acetylgalactosamine, N-acetylglucosamine, and sialic acid as its principal sugars in a ratio of 2:1:1:2, but with a small amount of glucose (2.3 mol %), mannose (1.2 mol %), and fucose (1.9 mol %).
Organism species: Homo sapiens (Human)
|CATALOG NO.||PRODUCT NAME||APPLICATIONS|
|Proteins||RPB710Hu01||Recombinant Glycocalicin (GC)||Positive Control; Immunogen; SDS-PAGE; WB.|
|Antibodies||PAB710Hu01||Polyclonal Antibody to Glycocalicin (GC)||WB; IHC; ICC; IP.|
|LAB710Hu71||Biotin-Linked Polyclonal Antibody to Glycocalicin (GC)||WB; IHC; ICC.|
|Assay Kits||SEB710Hu||ELISA Kit for Glycocalicin (GC)||Enzyme-linked immunosorbent assay for Antigen Detection.|