Glucose Transporter 4 (GLUT4)

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SLC2A4; Solute carrier family 2, facilitated glucose transporter member 4; Glucose transporter type 4, insulin-responsive

Glucose Transporter 4 (GLUT4)
GLUT4 is the insulin-regulated glucose transporter found in adipose tissues and striated muscle (skeletal and cardiac) that is responsible for insulin-regulated glucose disposal.In the absence of insulin, GLUT4 is sequestered in the interior of muscle and fat cells within lipid bilayers of vesicles. Insulin induces the translocation of GLUT4 from intracellular storage sites to the plasma membrane. Insulin binds to the insulin receptor in its dimeric form.
The receptor phosphorylates and subsequently activates IRS-1, which converts PIP2 to PIP3. PIP3 is bound to PKB (protein kinase B), signaling for PDK1 to phosphorylate PKB. Once phosphorylated, PKB is in its active form and phosphorylates other targets that stimulate GLUT4 to be expressed on the plasma membrane.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC023Hu01Recombinant Glucose Transporter 4 (GLUT4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC023Hu01Polyclonal Antibody to Glucose Transporter 4 (GLUT4)WB, ICC, IHC-P, IHC-F, ELISA
MAC023Hu22Monoclonal Antibody to Glucose Transporter 4 (GLUT4)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC023HuELISA Kit for Glucose Transporter 4 (GLUT4)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC023Mu01Recombinant Glucose Transporter 4 (GLUT4)SDS-PAGE; WB; ELISA; IP.
RPC023Mu02Recombinant Glucose Transporter 4 (GLUT4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC023Mu01Polyclonal Antibody to Glucose Transporter 4 (GLUT4)WB, ICC, IHC-P, IHC-F, ELISA
PAC023Mu02Polyclonal Antibody to Glucose Transporter 4 (GLUT4)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC023MuELISA Kit for Glucose Transporter 4 (GLUT4)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC023Ra01Recombinant Glucose Transporter 4 (GLUT4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC023Ra01Polyclonal Antibody to Glucose Transporter 4 (GLUT4)WB, ICC, IHC-P, IHC-F, ELISA
MAC023Ra21Monoclonal Antibody to Glucose Transporter 4 (GLUT4)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC023RaELISA Kit for Glucose Transporter 4 (GLUT4)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPC023Ca01Recombinant Glucose Transporter 4 (GLUT4)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC023Ca01Polyclonal Antibody to Glucose Transporter 4 (GLUT4)WB, ICC, IHC-P, IHC-F, ELISA
MAC023Ca21Monoclonal Antibody to Glucose Transporter 4 (GLUT4)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC023CaELISA Kit for Glucose Transporter 4 (GLUT4)Enzyme-linked immunosorbent assay for Antigen Detection
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