Butyrylcholinesterase (BCHE)


BuChE; CHE1; E1; Pseudocholinesterase; Cholinesterase; Acylcholine acylhydrolase; Butyrylcholine esterase; Choline esterase II

Butyrylcholinesterase (BCHE)
Mutant alleles at the BCHE locus are responsible for suxamethonium sensitivity. Homozygous persons sustain prolonged apnea after administration of the muscle relaxant suxamethonium in connection with surgical anesthesia. The activity of pseudocholinesterase in the serum is low and its substrate behavior is atypical. Butyrylcholinesterase is believed to play a role in the body's ability to metabolize the drug cocaine. In 2008, an experimental new drug was discovered for the potential treatment of cocaine abuse and overdose based on the BChE structure. It was shown to remove cocaine from the body 2000 times as fast as the natural form of BChE. Studies in rats have shown that the drug prevented convulsions and death when administered cocaine overdoses.

Organism species: Homo sapiens (Human)

ProteinsRPC348Hu01Recombinant Butyrylcholinesterase (BCHE)SDS-PAGE; WB; ELISA; IP.
RPC348Hu02Recombinant Butyrylcholinesterase (BCHE)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC348Hu01Polyclonal Antibody to Butyrylcholinesterase (BCHE)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
MAC348Hu22Monoclonal Antibody to Butyrylcholinesterase (BCHE)WB, ICC, IHC-P, IHC-F, ELISA
PAC348Hu02Polyclonal Antibody to Butyrylcholinesterase (BCHE)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC348HuELISA Kit for Butyrylcholinesterase (BCHE)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Mus musculus (Mouse)

Proteinsn/aRecombinant Butyrylcholinesterase (BCHE)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Butyrylcholinesterase (BCHE)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Butyrylcholinesterase (BCHE)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Butyrylcholinesterase (BCHE)CLIA Kit Customized Service Offer
n/aELISA Kit for Butyrylcholinesterase (BCHE)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

ProteinsRPC348Ra01Recombinant Butyrylcholinesterase (BCHE)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAC348Ra01Polyclonal Antibody to Butyrylcholinesterase (BCHE)WB, ICC, IHC-P, IHC-F, ELISA
MAC348Ra21Monoclonal Antibody to Butyrylcholinesterase (BCHE)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEC348RaELISA Kit for Butyrylcholinesterase (BCHE)Enzyme-linked immunosorbent assay for Antigen Detection
CEC348RaELISA Kit for Butyrylcholinesterase (BCHE)Enzyme-linked immunosorbent assay for Antigen Detection
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