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Collapsin Response Mediator Protein 1 (CRMP1)

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DPYSL1; DRP1; Dihydropyrimidinase Like 1; Dihydropyrimidinase-related protein 1; Unc-33-like phosphoprotein 3

Collapsin Response Mediator Protein 1 (CRMP1)
CCC C404
HGNC 2365
MGI 107793
PubMed 22798627
RGD 2407
UniProt Q14194
Wiki CRMP1

Collapsin response mediator protein 1 is a member of a family of cytosolic phosphoproteins expressed exclusively in the nervous system. The encoded protein is thought to be a part of the semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. Alternative splicing results in multiple transcript variants.

CRMP1 mediates reelin signaling in cortical neuronal migration. Mice deficient in CRMP1 exhibit impaired long-term potentiation and impaired spatial learning and memory.CRMP1 gene overlaps with another gene called EVC.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC404Hu01 Recombinant Collapsin Response Mediator Protein 1 (CRMP1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC404Hu01 Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Collapsin Response Mediator Protein 1 (CRMP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Collapsin Response Mediator Protein 1 (CRMP1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Collapsin Response Mediator Protein 1 (CRMP1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Collapsin Response Mediator Protein 1 (CRMP1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Collapsin Response Mediator Protein 1 (CRMP1) ELISA Kit Customized Service Offer
  1. "A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution."Gene 180:157-163(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Long form collapsin response mediator protein-1 (LCRMP-1) expression is associated with clinical outcome and lymph node metastasis in non-small cell lung cancer patients."Lung Cancer 67:93-100(2010) [PubMed] [Europe PMC] [Abstract]
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Genomic organization and localization of the human CRMP-1 gene."DNA Res. 5:393-395(1998) [PubMed] [Europe PMC] [Abstract]
  6. "Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33."Nature 376:509-514(1995) [PubMed] [Europe PMC] [Abstract]
  7. , Submitted (DEC-2008) to UniProtKB
  8. "Brain CRMP forms heterotetramers similar to liver dihydropyrimidinase."J. Neurochem. 69:2261-2269(1997) [PubMed] [Europe PMC] [Abstract]
  9. "Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells."J. Natl. Cancer Inst. 93:1392-1400(2001) [PubMed] [Europe PMC] [Abstract]
  10. "From midbody protein-protein interaction network construction to novel regulators in cytokinesis."J. Proteome Res. 8:4943-4953(2009) [PubMed] [Europe PMC] [Abstract]