Calmegin (CLGN)

Calmegin, also known as CLGN, is a protein which in humans is encoded by the CLGN gene. Calmegin is also present in other animals including mice.Calmegin is a testis-specific endoplasmic reticulum chaperone protein. CLGN may play a role in spermatogeneisis and infertility.

The proper folding of newly synthesized membrane proteins in the endoplasmic reticulum (ER) is required for the formation of functional mature proteins. Calmegin is similar to calnexin, a ubiquitous ER chaperone that plays a major role in quality control by retaining incompletely folded or misfolded proteins. In contrast to other known chaperones, such as heat shock proteins and calreticulin, calnexin is an integral membrane protein .

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC415Hu01 Recombinant Calmegin (CLGN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Calmegin (CLGN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calmegin (CLGN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calmegin (CLGN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calmegin (CLGN) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calmegin (CLGN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calmegin (CLGN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calmegin (CLGN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calmegin (CLGN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calmegin (CLGN) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Calmegin (CLGN) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Calmegin (CLGN) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Calmegin (CLGN) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Calmegin (CLGN) CLIA Kit Customized Service Offer
n/a ELISA Kit for Calmegin (CLGN) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of the human Calmegin gene encoding putative testis-specific chaperone."Gene 204:159-163(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
  5. "A developmentally regulated chaperone complex for the endoplasmic reticulum of male haploid germ cells."Mol. Biol. Cell 18:2795-2804(2007) [PubMed] [Europe PMC] [Abstract]
  6. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]