Vasoactive Intestinal Peptide Receptor 1 (VIPR1)

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HVR1; PACAP-R-2; RDC1; VAPC1; VIPR; VIRG; VPAC1; Pituitary adenylate cyclase-activating polypeptide type II receptor

Vasoactive Intestinal Peptide Receptor 1 (VIPR1)
Vasoactive intestinal peptide receptor 1 is expressed in the brain (cerebral cortex, hippocampus, amygdala), lung, prostate, peripheral blood leukocytes, liver, small intestine, heart, spleen, placenta, kidney, thymus and testis .
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC596Hu01 Recombinant Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC596Hu01 Polyclonal Antibody to Vasoactive Intestinal Peptide Receptor 1 (VIPR1) WB; IHC; ICC; IP.
MAC596Hu22 Monoclonal Antibody to Vasoactive Intestinal Peptide Receptor 1 (VIPR1) WB; IHC; ICC; IP.
Assay Kits SEC596Hu ELISA Kit for Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vasoactive Intestinal Peptide Receptor 1 (VIPR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vasoactive Intestinal Peptide Receptor 1 (VIPR1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC596Ra01 Recombinant Vasoactive Intestinal Peptide Receptor 1 (VIPR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC596Ra01 Polyclonal Antibody to Vasoactive Intestinal Peptide Receptor 1 (VIPR1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Vasoactive Intestinal Peptide Receptor 1 (VIPR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vasoactive Intestinal Peptide Receptor 1 (VIPR1) ELISA Kit Customized Service Offer
  1. "Cloning and functional expression of a human neuroendocrine vasoactive intestinal peptide receptor."Biochem. Biophys. Res. Commun. 193:546-553(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Human intestinal VIP receptor: cloning and functional expression of two cDNA encoding proteins with different N-terminal domains."Biochem. Biophys. Res. Commun. 200:769-776(1994) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Molecular cloning and functional characterization of a human liver vasoactive intestinal peptide receptor."Cell. Signal. 6:321-333(1994) [PubMed] [Europe PMC] [Abstract]
  7. "Highly conserved aspartate 68, tryptophan 73 and glycine 109 in the N-terminal extracellular domain of the human VIP receptor are essential for its ability to bind VIP."Biochem. Biophys. Res. Commun. 206:246-252(1995) [PubMed] [Europe PMC] [Abstract]
  8. "Predominant expression of type II vasoactive intestinal peptide receptors by human T lymphoblastoma cells: transduction of both Ca2+ and cyclic AMP signals."J. Clin. Immunol. 16:21-30(1996) [PubMed] [Europe PMC] [Abstract]
  9. "Importance of conserved cysteines in the extracellular loops of human PACAP/VIP1 receptor for ligand binding and stimulation of cAMP production."Ann. N. Y. Acad. Sci. 865:259-265(1998) [PubMed] [Europe PMC] [Abstract]
  10. "Dual, HLA-B27 subtype-dependent conformation of a self-peptide."J. Exp. Med. 199:271-281(2004) [PubMed] [Europe PMC] [Abstract]
  11. "Citrullination-dependent differential presentation of a self-peptide by HLA-B27 subtypes."J. Biol. Chem. 283:27189-27199(2008) [PubMed] [Europe PMC] [Abstract]