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Moesin (MSN)

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Membrane-Organizing Extension Spike Protein

Moesin (MSN)
CCC C642
HGNC 7373
MGI 97167
PubMed 22433855
RGD 621260
UniProt P26038
Wiki Moesin
Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.
Moesin is widely expressed in different tissues in cells, where it is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.which represents a single 4.2-kb mRNA encoding a protein of 577 amino acids. It contains no apparent signal peptide or transmembrane domain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC642Hu01 Recombinant Moesin (MSN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC642Hu02 Recombinant Moesin (MSN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC642Hu01 Polyclonal Antibody to Moesin (MSN) WB; IHC; ICC; IP.
MAC642Hu22 Monoclonal Antibody to Moesin (MSN) WB; IHC; ICC; IP.
PAC642Hu02 Polyclonal Antibody to Moesin (MSN) WB; IHC; ICC; IP.
Assay Kits SEC642Hu ELISA Kit for Moesin (MSN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Moesin (MSN) Recombinant Protein Customized Service Offer
Antibodies PAC642Mu01 Polyclonal Antibody to Moesin (MSN) WB; IHC; ICC; IP.
Assay Kits SEC642Mu ELISA Kit for Moesin (MSN) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC642Ra01 Recombinant Moesin (MSN) Positive Control; Immunogen; SDS-PAGE; WB.
RPC642Ra02 Recombinant Moesin (MSN) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC642Ra01 Polyclonal Antibody to Moesin (MSN) WB; IHC; ICC; IP.
PAC642Ra02 Polyclonal Antibody to Moesin (MSN) WB; IHC; ICC; IP.
Assay Kits SEC642Ra ELISA Kit for Moesin (MSN) Enzyme-linked immunosorbent assay for Antigen Detection.
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  5. "Identification of EBP50: a PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family."J. Cell Biol. 139:169-179(1997) [PubMed] [Europe PMC] [Abstract]
  6. "ITAM-based interaction of ERM proteins with Syk mediates signaling by the leukocyte adhesion receptor PSGL-1."Immunity 17:401-412(2002) [PubMed] [Europe PMC] [Abstract]
  7. "TIMAP is a positive regulator of pulmonary endothelial barrier function."Am. J. Physiol. 295:L440-L450(2008) [PubMed] [Europe PMC] [Abstract]
  8. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  9. "LOK is a major ERM kinase in resting lymphocytes and regulates cytoskeletal rearrangement through ERM phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 106:4707-4712(2009) [PubMed] [Europe PMC] [Abstract]
  10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  12. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  13. "PDZD8 is a novel moesin-interacting cytoskeletal regulatory protein that suppresses infection by herpes simplex virus type 1."Virology 415:114-121(2011) [PubMed] [Europe PMC] [Abstract]
  14. "N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB."Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012) [PubMed] [Europe PMC] [Abstract]
  15. "Target-selective protein S-nitrosylation by sequence motif recognition."Cell 159:623-634(2014) [PubMed] [Europe PMC] [Abstract]
  16. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  17. "Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domain."Cell 101:259-270(2000) [PubMed] [Europe PMC] [Abstract]
  18. "The 2.7 A crystal structure of the activated FERM domain of moesin: an analysis of structural changes on activation."Biochemistry 40:7061-7068(2001) [PubMed] [Europe PMC] [Abstract]
  19. "The EBP50-moesin interaction involves a binding site regulated by direct masking on the FERM domain."J. Cell Sci. 117:1547-1552(2004) [PubMed] [Europe PMC] [Abstract]