Progestagen Associated Endometrial Protein (PAEP)

[Edit]

GD; GdA; GdF; GdS; PAEG; PEP; PP14; Glycodelin; Placental Protein 14; Alpha Uterine Protein; Pregnancy-Associated Endometrial Alpha-2-Globulin; Progesterone-associated

Progestagen Associated Endometrial Protein (PAEP)
Glycodelin is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9.
The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC709Hu01 Recombinant Progestagen Associated Endometrial Protein (PAEP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC709Hu01 Polyclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) WB; IHC; ICC; IP.
MAC709Hu22 Monoclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) WB; IHC; ICC; IP.
Assay Kits SEC709Hu ELISA Kit for Progestagen Associated Endometrial Protein (PAEP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Progestagen Associated Endometrial Protein (PAEP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Progestagen Associated Endometrial Protein (PAEP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Progestagen Associated Endometrial Protein (PAEP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Progestagen Associated Endometrial Protein (PAEP) ELISA Kit Customized Service Offer
  1. "Complete amino acid sequence of human placental protein 14: a progesterone-regulated uterine protein homologous to beta-lactoglobulins."Proc. Natl. Acad. Sci. U.S.A. 85:8845-8849(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Human placental protein 14 gene: sequence and characterization of a short duplication."DNA Cell Biol. 9:401-413(1990) [PubMed] [Europe PMC] [Abstract]
  3. "Multiple forms of mRNA encoding human pregnancy-associated endometrial alpha 2-globulin, a beta-lactoglobulin homologue."Proc. Natl. Acad. Sci. U.S.A. 88:2456-2460(1991) [PubMed] [Europe PMC] [Abstract]
  4. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  5. "DNA sequence and analysis of human chromosome 9." Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  7. "Pregnancy-associated endometrial alpha 2-globulin, the major secretory protein of the luteal phase and first trimester pregnancy endometrium, is not glycosylated prolactin but related to beta-lactoglobulins."J. Clin. Endocrinol. Metab. 65:1067-1071(1987) [PubMed] [Europe PMC] [Abstract]
  8. "Amino acid sequence homology between human placental protein 14 and beta-lactoglobulins from various species."Endocrinology 120:2620-2622(1987) [PubMed] [Europe PMC] [Abstract]
  9. "Purification and characterization of an immunomodulatory endometrial protein, glycodelin."J. Biol. Chem. 276:17101-17105(2001) [PubMed] [Europe PMC] [Abstract]
  10. "Structural analysis of the oligosaccharides derived from glycodelin, a human glycoprotein with potent immunosuppressive and contraceptive activities."J. Biol. Chem. 270:24116-24126(1995) [PubMed] [Europe PMC] [Abstract]
  11. "Gender-specific glycosylation of human glycodelin affects its contraceptive activity."J. Biol. Chem. 271:32159-32167(1996) [PubMed] [Europe PMC] [Abstract]
  12. "Glycodelin from seminal plasma is a differentially glycosylated form of contraceptive glycodelin-A."Mol. Hum. Reprod. 2:759-765(1996) [PubMed] [Europe PMC] [Abstract]