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Poly ADP Ribose Polymerase 4 (PARP4)

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ADPRTL1; ARTD4; PARPL; PH5P; VAULT3; VPARP; P193; VWA5C; von Willebrand Factor A Domain Containing 5C; ADP-ribosyltransferase diphtheria toxin-like 4; Vault polymerase

Poly ADP Ribose Polymerase 4 (PARP4)
CCC C984
HGNC 271
MGI 2685589
PubMed 10644454
RGD 1310524
UniProt Q9UKK3
Wiki PARP4
Poly [ADP-ribose] polymerase 4 is an enzyme encoded by the PARP4 gene.This gene encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction.
This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC984Hu01 Recombinant Poly ADP Ribose Polymerase 4 (PARP4) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC984Hu01 Polyclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4) WB; IHC; ICC; IP.
MAC984Hu22 Monoclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4) WB; IHC; ICC; IP.
Assay Kits SEC984Hu ELISA Kit for Poly ADP Ribose Polymerase 4 (PARP4) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Poly ADP Ribose Polymerase 4 (PARP4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Poly ADP Ribose Polymerase 4 (PARP4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Poly ADP Ribose Polymerase 4 (PARP4) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Poly ADP Ribose Polymerase 4 (PARP4) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Poly ADP Ribose Polymerase 4 (PARP4) CLIA Kit Customized Service Offer
n/a ELISA Kit for Poly ADP Ribose Polymerase 4 (PARP4) ELISA Kit Customized Service Offer
  1. "The 193 kDa vault protein, VPARP, is a novel poly(ADP-ribose) polymerase."J. Cell Biol. 146:917-928(1999) [PubMed] [Europe PMC] [Abstract]
  2. "Identification of a novel gene (ADPRTL1) encoding a potential poly(ADP-ribosyl)transferase protein."Genomics 62:533-536(1999) [PubMed] [Europe PMC] [Abstract]
  3. "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1."DNA Res. 3:17-24(1996) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair?"FEBS Lett. 446:6-8(1999) [PubMed] [Europe PMC] [Abstract]
  6. "Vaults and telomerase share a common subunit, TEP1."J. Biol. Chem. 274:32712-32717(1999) [PubMed] [Europe PMC] [Abstract]
  7. "A quantitative atlas of mitotic phosphorylation."Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]
  8. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  9. "Toward a unified nomenclature for mammalian ADP-ribosyltransferases."Trends Biochem. Sci. 35:208-219(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  11. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]