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Isoleucyl tRNA Synthetase (IARS)

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IARS1; ILRS; OJ; IleRS; IRS; Isoleucine tRNA Ligase 1,Cytoplasmic

Isoleucyl tRNA Synthetase (IARS)
CCC D004
HGNC 5330
MGI 2145219
PubMed 7929087
RGD 621022
UniProt P41252
Wiki IARS
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution.
Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Two alternatively spliced variants have been isolated that represent alternate 5' UTRs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD004Hu01 Recombinant Isoleucyl tRNA Synthetase (IARS) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD004Hu01 Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC
MAD004Hu21 Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) WB; IHC; ICC; IP.
Assay Kits SED004Hu ELISA Kit for Isoleucyl tRNA Synthetase (IARS) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Isoleucyl tRNA Synthetase (IARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Isoleucyl tRNA Synthetase (IARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Isoleucyl tRNA Synthetase (IARS) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Isoleucyl tRNA Synthetase (IARS) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Isoleucyl tRNA Synthetase (IARS) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Isoleucyl tRNA Synthetase (IARS) CLIA Kit Customized Service Offer
n/a ELISA Kit for Isoleucyl tRNA Synthetase (IARS) ELISA Kit Customized Service Offer
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  2. "Human isoleucyl-tRNA synthetase: sequence of the cDNA, alternative mRNA splicing, and the characteristics of an unusually long C-terminal extension."Gene 155:299-304(1995) [PubMed] [Europe PMC] [Abstract]
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