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Hemoglobin Alpha 1 (HBa1)

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Alpha-globin

Hemoglobin Alpha 1 (HBa1)
CCC D090
HGNC 4823
MGI 96016
PubMed 3391093
RGD 2782
UniProt P69905
Wiki HBA1

The human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD090Hu01 Recombinant Hemoglobin Alpha 1 (HBa1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD090Hu01 Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB; IHC; ICC; IP.
LAD090Hu71 Biotin-Linked Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB; IHC; ICC.
LAD090Hu81 FITC-Linked Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB; IHC; ICC; IF.
MAD090Hu21 Monoclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB,IHC
MAD090Hu22 Monoclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB,IHC
MAD090Hu23 Monoclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB; IHC; ICC; IP.
Assay Kits SED090Hu ELISA Kit for Hemoglobin Alpha 1 (HBa1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD090Mu01 Recombinant Hemoglobin Alpha 1 (HBa1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD090Mu01 Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB,IHC
Assay Kits n/a CLIA Kit for Hemoglobin Alpha 1 (HBa1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hemoglobin Alpha 1 (HBa1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hemoglobin Alpha 1 (HBa1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hemoglobin Alpha 1 (HBa1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hemoglobin Alpha 1 (HBa1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hemoglobin Alpha 1 (HBa1) ELISA Kit Customized Service Offer

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Hemoglobin Alpha 1 (HBa1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Hemoglobin Alpha 1 (HBa1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hemoglobin Alpha 1 (HBa1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hemoglobin Alpha 1 (HBa1) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD090Bo01 Recombinant Hemoglobin Alpha 1 (HBa1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD090Bo01 Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB
Assay Kits n/a CLIA Kit for Hemoglobin Alpha 1 (HBa1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hemoglobin Alpha 1 (HBa1) ELISA Kit Customized Service Offer

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NPD090Cp01 Native Hemoglobin Alpha 1 (HBa1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Hemoglobin Alpha 1 (HBa1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Hemoglobin Alpha 1 (HBa1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hemoglobin Alpha 1 (HBa1) ELISA Kit Customized Service Offer

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPD090Eq01 Recombinant Hemoglobin Alpha 1 (HBa1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAD090Eq01 Polyclonal Antibody to Hemoglobin Alpha 1 (HBa1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Hemoglobin Alpha 1 (HBa1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Hemoglobin Alpha 1 (HBa1) ELISA Kit Customized Service Offer
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  65. "Hb Aghia Sophia [alpha62(E11)Val-->0 (alpha1)], an 'in-frame' deletion causing alpha-thalassemia."Hemoglobin 23:317-324(1999) [PubMed] [Europe PMC] [Abstract]
  66. "Two new alpha chain variants: Hb Boghe [alpha58(E7)His-->Gln, alpha2], a variant on the distal histidine, and Hb Charolles [alpha103(G10)His-Tyr, alpha1]."Hemoglobin 23:345-352(1999) [PubMed] [Europe PMC] [Abstract]
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  68. "Characterization of hemoglobin Bassett (alpha94Asp-->Ala), a variant with very low oxygen affinity."Am. J. Hematol. 77:268-276(2004) [PubMed] [Europe PMC] [Abstract]
  69. "A novel mutation of the alpha2-globin causing alpha(+)-thalassemia: Hb Plasencia [alpha125(H8)Leu-->Arg (alpha2)."Hemoglobin 29:113-117(2005) [PubMed] [Europe PMC] [Abstract]