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Motilin Receptor (MLNR)

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GPR38; MLNR; MTLR1; G Protein-Coupled Receptor 38

Motilin Receptor (MLNR)
CCC D253
HGNC 4495
PubMed 18183601
UniProt O43193
Wiki MLNR
Motilin receptor is a G protein-coupled receptor that binds motilin. Motilin in turn is an intestinal peptide that stimulates contraction of gut smooth muscle.
The growth hormone secretagogue receptor (GHSR) is a G protein-coupled receptor found in the pituitary gland and brain that is involved in the control of growth hormone release. McKee et al. identified 2 human genes related to GHSR: GPR38 and GPR39. The predicted 438-amino acid GPR38 protein contains the 7 transmembrane domains characteristic of G protein-coupled receptors. The amino acid sequences of GPR38 and GSHR are 52% identical. RNase protection studies revealed that GPR38 is expressed only in thyroid, stomach, and bone marrow.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Motilin Receptor (MLNR) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Motilin Receptor (MLNR) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Motilin Receptor (MLNR) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Motilin Receptor (MLNR) CLIA Kit Customized Service Offer
n/a ELISA Kit for Motilin Receptor (MLNR) ELISA Kit Customized Service Offer
  1. "Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors."Genomics 46:426-434(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Receptor for motilin identified in the human gastrointestinal system." Science 284:2184-2188(1999) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 13." Nature 428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Growth hormone secretagogue receptor family members and ligands."Endocrine 14:9-14(2001) [PubMed] [Europe PMC] [Abstract]