Aldolase B, Fructose Bisphosphate (ALDOB)

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ALDO-BL; Liver-type aldolase

Aldolase B, Fructose Bisphosphate (ALDOB)
Aldolase B is an isoenzyme of fructose 1,6-bisphosphate aldolase (aldolase A), which is also capable of cleaving fructose 1-phosphate to form glyceraldehyde and dihydroxyacetone phosphate (DHAP). The reaction is reversible. Also known as Aldolase (Class I), it is found in the liver and kidney.
Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13 ) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Defects of aldolase B cause fructose 1-phosphate to accumulate in tissues which contain fructokinase, a condition known as hereditary fructose intolerance.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPD319Hu01Recombinant Aldolase B, Fructose Bisphosphate (ALDOB)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAD319Hu01Polyclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB)WB, ICC, IHC-P, IHC-F, ELISA
MAD319Hu21Monoclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSED319HuELISA Kit for Aldolase B, Fructose Bisphosphate (ALDOB)Enzyme-linked immunosorbent assay

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Aldolase B, Fructose Bisphosphate (ALDOB)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Aldolase B, Fructose Bisphosphate (ALDOB)CLIA Kit Customized Service Offer
n/aELISA Kit for Aldolase B, Fructose Bisphosphate (ALDOB)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPD319Ra01Recombinant Aldolase B, Fructose Bisphosphate (ALDOB)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAD319Ra01Polyclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB)WB, ICC, IHC-P, IHC-F, ELISA
MAD319Ra21Monoclonal Antibody to Aldolase B, Fructose Bisphosphate (ALDOB)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSED319RaELISA Kit for Aldolase B, Fructose Bisphosphate (ALDOB)Enzyme-linked immunosorbent assay
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  21. "Molecular analysis of the aldolase B gene in patients with hereditary fructose intolerance from Spain."J. Med. Genet. 39:E56-E56(2002) [PubMed] [Europe PMC] [Abstract]
  22. "Six novel alleles identified in Italian hereditary fructose intolerance patients enlarge the mutation spectrum of the aldolase B gene."Hum. Mutat. 24:534-534(2004) [PubMed] [Europe PMC] [Abstract]
  23. "The spectrum of aldolase B (ALDOB) mutations and the prevalence of hereditary fructose intolerance in Central Europe."Hum. Mutat. 25:594-594(2005) [PubMed] [Europe PMC] [Abstract]