Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)

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BPTP3; CFC; NS1; PTP-1D; PTP2C; SH-PTP2; SH-PTP3; SHP2; Noonan Syndrome 1; Protein-tyrosine phosphatase 1D; Protein-tyrosine phosphatase 2C

Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)
PTPN11 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates.
This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)CLIA Kit Customized Service Offer
n/aELISA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)CLIA Kit Customized Service Offer
n/aELISA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPD584Ra01Recombinant Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAD584Ra01Polyclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)WB, ICC, IHC-P, IHC-F, ELISA
MAD584Ra21Monoclonal Antibody to Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSED584RaELISA Kit for Protein Tyrosine Phosphatase, Non Receptor Type 11 (PTPN11)Enzyme-linked immunosorbent assay
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  45. ErratumNat. Genet. 29:491-491(2001)
  46. ErratumNat. Genet. 30:123-123(2001)
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  53. ErratumEur. J. Hum. Genet. 11:551-551(2003)
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