Glucose Transporter 10 (GLUT10)

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SLC2A10; ATS; Solute Carrier Family 2 Member 10,Facilitated Glucose Transporter

Glucose Transporter 10 (GLUT10)
SLC2A10 is a member of the facilitative glucose transporter family, which plays a significant role in maintaining glucose homeostasis. a full-length SLC2A10 cDNA encoding a 541-amino acid protein. SLC2A10 shares between approximately 28% (SLC2A3) and 34% (SLC2A8) amino acid sequence identity with other members of the facilitative glucose transporter family. SLC2A10 has 12 transmembrane domains, with a hydrophilic intracellular loop between helices 6 and 7, together with a large extracellular loop (containing a potential N-linked glycosylation site) between helices 9 and 10. Northern blot analysis of adult tissues detected a major 4.3-kb transcript with highest levels of expression in liver and pancreas and lower levels of expression in all other tissues examined.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Glucose Transporter 10 (GLUT10)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Glucose Transporter 10 (GLUT10)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Glucose Transporter 10 (GLUT10)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Glucose Transporter 10 (GLUT10)CLIA Kit Customized Service Offer
n/aELISA Kit for Glucose Transporter 10 (GLUT10)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Glucose Transporter 10 (GLUT10)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Glucose Transporter 10 (GLUT10)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Glucose Transporter 10 (GLUT10)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Glucose Transporter 10 (GLUT10)CLIA Kit Customized Service Offer
n/aELISA Kit for Glucose Transporter 10 (GLUT10)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Glucose Transporter 10 (GLUT10)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Glucose Transporter 10 (GLUT10)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Glucose Transporter 10 (GLUT10)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Glucose Transporter 10 (GLUT10)CLIA Kit Customized Service Offer
n/aELISA Kit for Glucose Transporter 10 (GLUT10)ELISA Kit Customized Service Offer
  1. "Molecular cloning of a novel member of the GLUT family of transporters, SLC2A10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility."Genomics 72:113-117(2001) [PubMed] [Europe PMC] [Abstract]
  2. "Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1."Mol. Genet. Metab. 74:186-199(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  6. "Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits."Diabetes 52:2445-2448(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome."Nat. Genet. 38:452-457(2006) [PubMed] [Europe PMC] [Abstract]
  8. "Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families." Hum. Mutat. 29:150-158(2008) [PubMed] [Europe PMC] [Abstract]