Vesicular Monoamine Transporter 2 (VMAT2)

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SLC18A2; SVMT; SVAT; Solute Carrier Family 18 Member 2,Vesicular Monoamine; Monoamine transporter; Synaptic vesicular amine transporter

Vesicular Monoamine Transporter 2 (VMAT2)
VMAT2 is an integral membrane protein that acts to transport monoamines—particularly neurotransmitters such as dopamine, norepinephrine, serotonin, and histamine—from cellular cytosol into synaptic vesicles. In humans, the VMAT2 protein is encoded by the VMAT2 gene. Geneticist Dean Hamer identified the VMAT2 gene as correlating with spirituality using data from a smoking survey, which included questions intended to measure "self-transcendence". Hamer performed the spirituality study on the side, independently of the National Cancer Institute smoking study. His findings were published in the mass-market book According to Carl Zimmer, Hamer's study has not been academically published and depends on minor statistical variance.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE389Hu01 Recombinant Vesicular Monoamine Transporter 2 (VMAT2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAE389Hu21 Monoclonal Antibody to Vesicular Monoamine Transporter 2 (VMAT2) WB; IHC; ICC; IP.
PAE389Hu01 Polyclonal Antibody to Vesicular Monoamine Transporter 2 (VMAT2) WB; IHC; ICC; IP.
Assay Kits SEE389Hu ELISA Kit for Vesicular Monoamine Transporter 2 (VMAT2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vesicular Monoamine Transporter 2 (VMAT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vesicular Monoamine Transporter 2 (VMAT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vesicular Monoamine Transporter 2 (VMAT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vesicular Monoamine Transporter 2 (VMAT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vesicular Monoamine Transporter 2 (VMAT2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Vesicular Monoamine Transporter 2 (VMAT2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Vesicular Monoamine Transporter 2 (VMAT2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Vesicular Monoamine Transporter 2 (VMAT2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Vesicular Monoamine Transporter 2 (VMAT2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Vesicular Monoamine Transporter 2 (VMAT2) ELISA Kit Customized Service Offer
  1. "A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs."FEBS Lett. 318:325-330(1993) [PubMed] [Europe PMC] [Abstract]
  2. "Functional identification and molecular cloning of a human brain vesicle monoamine transporter."J. Neurochem. 61:2314-2317(1993) [PubMed] [Europe PMC] [Abstract]
  3. "Chromosomal localization of the human vesicular amine transporter genes."Genomics 18:720-723(1993) [PubMed] [Europe PMC] [Abstract]
  4. "Extensive sequence divergence between the human and rat brain vesicular monoamine transporter: possible molecular basis for species differences in the susceptibility to MPP+."J. Neural Transm. 93:75-82(1993) [PubMed] [Europe PMC] [Abstract]
  5. "Exon/intron boundaries, novel polymorphisms, and association analysis with schizophrenia of the human synaptic vesicle monoamine transporter (SVMT) gene."Mol. Psychiatry 6:456-460(2001) [PubMed] [Europe PMC] [Abstract]
  6. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  7. "The DNA sequence and comparative analysis of human chromosome 10." Nature 429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  9. "Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines that form an intramolecular disulfide bond."Biochemistry 41:6346-6353(2002) [PubMed] [Europe PMC] [Abstract]
  10. "Phosphoproteome of resting human platelets."J. Proteome Res. 7:526-534(2008) [PubMed] [Europe PMC] [Abstract]