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Complement Component 1, Q Subcomponent C (C1qC)

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C1QG; Complement Component 1 q subcomponent,Gamma Polypeptide

Complement Component 1, Q Subcomponent C (C1qC)
CCC E869
HGNC 1245
MGI 88225
RGD 1306828
UniProt P02747
C1qCencodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis.
C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE869Hu01 Recombinant Complement Component 1, Q Subcomponent C (C1qC) Positive Control; Immunogen; SDS-PAGE; WB.
APE869Hu01 Active Complement Component 1, Q Subcomponent C (C1qC) Cell culture; Activity Assays.
Antibodies PAE869Hu01 Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) WB; IHC; ICC; IP.
MAE869Hu21 Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) WB; IHC; ICC; IP.
Assay Kits SEE869Hu ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) Enzyme-linked immunosorbent assay for Antigen Detection.
SCE869Hu CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Complement Component 1, Q Subcomponent C (C1qC) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPE869Ra01 Recombinant Complement Component 1, Q Subcomponent C (C1qC) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Complement Component 1, Q Subcomponent C (C1qC) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Complement Component 1, Q Subcomponent C (C1qC) CLIA Kit Customized Service Offer
n/a ELISA Kit for Complement Component 1, Q Subcomponent C (C1qC) ELISA Kit Customized Service Offer
  1. "Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q."Biochem. J. 274:481-490(1991) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and biological annotation of human chromosome 1." Nature 441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement."Biochem. J. 179:367-371(1979) [PubMed] [Europe PMC] [Abstract]
  6. "The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties."J. Biol. Chem. 278:46974-46982(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Molecular basis of hereditary C1q deficiency."Immunobiology 199:286-294(1998) [PubMed] [Europe PMC] [Abstract]
  8. "Homozygous hereditary C1q deficiency and systemic lupus erythematosus. A new family and the molecular basis of C1q deficiency in three families."Arthritis Rheum. 39:663-670(1996) [PubMed] [Europe PMC] [Abstract]