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Nuclear Receptor Corepressor 1 (NCOR1)

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KIAA1047; N-CoR; TRAC1; hN-CoR; Thyroid Hormone And Retinoic Acid Receptor Associated Corepressor 1

Nuclear Receptor Corepressor 1 (NCOR1)
CCC F100
HGNC 7672
MGI 1349717
PubMed 23610395
RGD 3612
UniProt O75376
Wiki NCOR1
nuclear receptor co-repressor 1 (NCOR1) appears to recruit histone deacetylases to DNA promoter regions. Hence NCOR1 assists nuclear receptors in the down regulation of DNA expression.
NCOR1is a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. An alternatively spliced transcript variant has been described, but its full length sequence has not been determined.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF100Hu01 Recombinant Nuclear Receptor Corepressor 1 (NCOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Corepressor 1 (NCOR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Corepressor 1 (NCOR1) Polyclonal Antibody Customized Service Offer
Assay Kits SEF100Hu ELISA Kit for Nuclear Receptor Corepressor 1 (NCOR1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF100Mu01 Recombinant Nuclear Receptor Corepressor 1 (NCOR1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Corepressor 1 (NCOR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Corepressor 1 (NCOR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Corepressor 1 (NCOR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Corepressor 1 (NCOR1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Nuclear Receptor Corepressor 1 (NCOR1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Nuclear Receptor Corepressor 1 (NCOR1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Nuclear Receptor Corepressor 1 (NCOR1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Nuclear Receptor Corepressor 1 (NCOR1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Nuclear Receptor Corepressor 1 (NCOR1) ELISA Kit Customized Service Offer
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