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Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3)

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CD203c; CD203-c; B10; NPP3; PD-IBETA; PDNP3; Phosphodiesterase I beta; Alkaline phosphodiesterase I; Nucleotide pyrophosphatase

Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3)
CCC F218
HGNC 3358
MGI 2143702
PubMed 23960081
RGD 708511
UniProt O14638
Wiki ENPP3
ENPP3 belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver.
The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells.Expressed in bile ducts, prostate, uterus and colon. Exclusively expressed on basophils, mast cells and their progenitors.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF218Hu01 Recombinant Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF218Hu01 Polyclonal Antibody to Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) WB; IHC; ICC; IP.
Assay Kits SEF218Hu ELISA Kit for Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF218Mu01 Recombinant Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF218Mu01 Polyclonal Antibody to Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) WB; IHC; ICC; IP.
Assay Kits SEF218Mu ELISA Kit for Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Ectonucleotide Pyrophosphatase/Phosphodiesterase 3 (ENPP3) ELISA Kit Customized Service Offer
  1. "Molecular cloning and chromosomal localization of PD-Ibeta (PDNP3), a new member of the human phosphodiesterase I genes."Genomics 45:412-415(1997) [PubMed] [Europe PMC] [Abstract]
  2. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The basophil activation marker defined by antibody 97A6 is identical to the ectonucleotide pyrophosphatase/phosphodiesterase 3."Blood 97:3303-3305(2001) [PubMed] [Europe PMC] [Abstract]
  5. "Expression and localization of ecto-nucleotide pyrophosphatase/phosphodiesterase I-1 (E-NPP1/PC-1) and -3 (E-NPP3/CD203c/PD-Ibeta/B10/gp130(RB13-6)) in inflammatory and neoplastic bile duct diseases."Cancer Lett. 207:139-147(2004) [PubMed] [Europe PMC] [Abstract]
  6. "The basophil-specific ectoenzyme E-NPP3 (CD203c) as a marker for cell activation and allergy diagnosis."Int. Arch. Allergy Immunol. 133:317-329(2004) [PubMed] [Europe PMC] [Abstract]