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Cysteine Rich Secretory Protein 3 (CRISP3)

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CRS3; Aeg2; CRISP-3; SGP28; Specific granule protein of 28 kDa

Cysteine Rich Secretory Protein 3 (CRISP3)
CCC F340
HGNC 16904
MGI 102553
PubMed 22993349
UniProt P54108
Wiki CRISP3
Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma.Human cysteine-rich secretory protein 3 (CRISP-3; also known as SGP28) belongs to a family of closely related proteins found in mammals and reptiles. Some mammalian CRISPs are known to be involved in the process of reproduction, whereas some of the CRISPs from reptiles are neurotoxin-like substances found in lizard saliva or snake venom. Human CRISP-3 is present in exocrine secretions and in secretory granules of neutrophilic granulocytes and is believed to play a role in innate immunity.
Electronic profiling of publicly available expressed sequence tag databases identified a gene, cysteine-rich secretoryprotein-3 (CRISP-3), that is up-regulated in prostate cancer, and of which the expression is relatively prostate-specific.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPF340Hu01 Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAF340Hu01 Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
MAF340Hu21 Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) WB; IHC; ICC; IP.
Assay Kits SEF340Hu ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Cysteine Rich Secretory Protein 3 (CRISP3) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Cysteine Rich Secretory Protein 3 (CRISP3) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) CLIA Kit Customized Service Offer
n/a ELISA Kit for Cysteine Rich Secretory Protein 3 (CRISP3) ELISA Kit Customized Service Offer
  1. "SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein."FEBS Lett. 380:246-250(1996) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and analysis of human chromosome 6." Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3."Eur. J. Biochem. 236:827-836(1996) [PubMed] [Europe PMC] [Abstract]
  6. "Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma."Biochemistry 43:12877-12886(2004) [PubMed] [Europe PMC] [Abstract]