Phosphatase And Tensin Homolog (PTEN)


BZS; MHAM; MMAC1; PTEN1; TEP1; Mutated In Multiple Advanced Cancers 1; Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

Phosphatase And Tensin Homolog (PTEN)
PTEN acts as a tumor suppressor gene through the action of its phosphatase protein product. This phosphatase is involved in the regulation of the cell cycle, preventing cells from growing and dividing too rapidly.This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating Akt/PKB signaling pathway.

Organism species: Homo sapiens (Human)

ProteinsRPF822Hu01Recombinant Phosphatase And Tensin Homolog (PTEN)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesPAF822Hu01Polyclonal Antibody to Phosphatase And Tensin Homolog (PTEN)WB; IHC; ICC; IP.
LAF822Hu71Biotin-Linked Polyclonal Antibody to Phosphatase And Tensin Homolog (PTEN)WB; IHC; ICC.
MAF822Hu21Monoclonal Antibody to Phosphatase And Tensin Homolog (PTEN)WB; IHC; ICC; IP.
Assay KitsSEF822HuELISA Kit for Phosphatase And Tensin Homolog (PTEN)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

ProteinsRPF822Mu01Recombinant Phosphatase And Tensin Homolog (PTEN)Positive Control; Immunogen; SDS-PAGE; WB.
RPF822Mu02Recombinant Phosphatase And Tensin Homolog (PTEN)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesPAF822Mu01Polyclonal Antibody to Phosphatase And Tensin Homolog (PTEN)WB; IHC; ICC; IP.
PAF822Mu02Polyclonal Antibody to Phosphatase And Tensin Homolog (PTEN)WB; IHC; ICC; IP.
Assay KitsSEF822MuELISA Kit for Phosphatase And Tensin Homolog (PTEN)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

ProteinsRPF822Ra01Recombinant Phosphatase And Tensin Homolog (PTEN)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesMAF822Ra21Monoclonal Antibody to Phosphatase And Tensin Homolog (PTEN)WB; IHC; ICC; IP.
PAF822Ra01Polyclonal Antibody to Phosphatase And Tensin Homolog (PTEN)WB; IHC; ICC; IP.
Assay KitsSEF822RaELISA Kit for Phosphatase And Tensin Homolog (PTEN)Enzyme-linked immunosorbent assay for Antigen Detection.
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