Syntaxin 16 (STX16)
STX16 encodes a protein that is a member of the syntaxin or t-SNARE (target-SNAP receptor) family. These proteins are found on cell membranes and serve as the targets for V-SNARES (vesicle-SNAP receptors) permitting specific synaptic vesicle docking and fusion. A microdeletion in the region of chromosome 20 where this gene is located has been associated with pseudohypoparathyroidism type Ib. Multiple transcript variants encoding different isoforms have been found for this gene. The predicted 307-amino acid protein contains the C-terminal hydrophobic tail anchor characteristic of syntaxins, and several potential coiled-coil regions. Using immunofluorescence, the authors determined that an epitope-tagged SYN16 protein localized to the Golgi apparatus.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Syntaxin 16 (STX16)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Syntaxin 16 (STX16)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Syntaxin 16 (STX16)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Syntaxin 16 (STX16)CLIA Kit Customized Service Offer
n/aELISA Kit for Syntaxin 16 (STX16)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Syntaxin 16 (STX16)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Syntaxin 16 (STX16)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Syntaxin 16 (STX16)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Syntaxin 16 (STX16)CLIA Kit Customized Service Offer
n/aELISA Kit for Syntaxin 16 (STX16)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Syntaxin 16 (STX16)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Syntaxin 16 (STX16)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Syntaxin 16 (STX16)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Syntaxin 16 (STX16)CLIA Kit Customized Service Offer
n/aELISA Kit for Syntaxin 16 (STX16)ELISA Kit Customized Service Offer
  1. "Syntaxin-16, a putative Golgi t-SNARE."Eur. J. Cell Biol. 75:223-231(1998) [PubMed] [Europe PMC] [Abstract]
  2. "Molecular cloning and localization of human syntaxin 16, a member of the syntaxin family of SNARE proteins."Biochem. Biophys. Res. Commun. 242:673-679(1998) [PubMed] [Europe PMC] [Abstract]
  3. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Autosomal dominant pseudohypoparathyroidism type Ib is associated with a heterozygous microdeletion that likely disrupts a putative imprinting control element of GNAS."J. Clin. Invest. 112:1255-1263(2003) [PubMed] [Europe PMC] [Abstract]
  6. "A novel STX16 deletion in autosomal dominant pseudohypoparathyroidism type Ib redefines the boundaries of a cis-acting imprinting control element of GNAS."Am. J. Hum. Genet. 76:804-814(2005) [PubMed] [Europe PMC] [Abstract]
  7. "A syntaxin 10-SNARE complex distinguishes two distinct transport routes from endosomes to the trans-Golgi in human cells."J. Cell Biol. 180:159-172(2008) [PubMed] [Europe PMC] [Abstract]