K-Acetyltransferase 2B (KAT2B)

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PCAF; P/CAF; GCN5; GCN5L; P300/CBP-Associated Factor; Histone acetyltransferase PCAF; Lysine acetyltransferase 2B

K-Acetyltransferase 2B (KAT2B)
Several domains of PCAF can act independently or in unison to enable its functions. PCAF has separate acetyltransferase and E3 ubiquitin ligase domains as well as a bromodomain for interaction with other proteins. PCAF also possesses sites for its own acetylation and ubiquitination.CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by the PCAF gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG189Hu01 Recombinant K-Acetyltransferase 2B (KAT2B) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG189Hu01 Polyclonal Antibody to K-Acetyltransferase 2B (KAT2B) WB; IHC; ICC; IP.
Assay Kits SEG189Hu ELISA Kit for K-Acetyltransferase 2B (KAT2B) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant K-Acetyltransferase 2B (KAT2B) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to K-Acetyltransferase 2B (KAT2B) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to K-Acetyltransferase 2B (KAT2B) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for K-Acetyltransferase 2B (KAT2B) CLIA Kit Customized Service Offer
n/a ELISA Kit for K-Acetyltransferase 2B (KAT2B) ELISA Kit Customized Service Offer
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