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Phosphoglycerate Kinase 1 (PGK1)

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MIG10; PGKA; PRP 2; Cell migration-inducing gene 10 protein; Primer recognition protein 2

Phosphoglycerate Kinase 1 (PGK1)
CCC G304
HGNC 8896
MGI 97555
PubMed 18453750
RGD 619878
UniProt P00558
Wiki PGK1
The Phosphoglycerate Kinase 1 is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. This gene lies on the X-chromosome, while a related pseudogene also has been found on the X-chromosome and another on chromosome 19.PGK1 is distinguished from testicular PGK2, which maps to chromosome 6p21.
The deduced protein contains 417 amino acid residues. Southern blot analysis of human genomic DNAs showed a complex pattern of hybridizing fragments, 2 of which were non-X in origin. The results were interpreted as reflecting the existence of a small family of dispersed PGK or PGK-like genes.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG304Hu01 Recombinant Phosphoglycerate Kinase 1 (PGK1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG304Hu01 Polyclonal Antibody to Phosphoglycerate Kinase 1 (PGK1) WB,IHC,ICC/IF
MAG304Hu21 Monoclonal Antibody to Phosphoglycerate Kinase 1 (PGK1) WB; IHC; ICC; IP.
Assay Kits SEG304Hu ELISA Kit for Phosphoglycerate Kinase 1 (PGK1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphoglycerate Kinase 1 (PGK1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphoglycerate Kinase 1 (PGK1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphoglycerate Kinase 1 (PGK1) Polyclonal Antibody Customized Service Offer
Assay Kits SEG304Mu ELISA Kit for Phosphoglycerate Kinase 1 (PGK1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Phosphoglycerate Kinase 1 (PGK1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Phosphoglycerate Kinase 1 (PGK1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Phosphoglycerate Kinase 1 (PGK1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Phosphoglycerate Kinase 1 (PGK1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Phosphoglycerate Kinase 1 (PGK1) ELISA Kit Customized Service Offer
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  9. , Submitted (DEC-2008) to UniProtKB
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  15. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
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  24. "Identification of new mutations in two phosphoglycerate kinase (PGK) variants expressing different clinical syndromes: PGK Creteil and PGK Amiens."Blood 84:898-903(1994) [PubMed] [Europe PMC] [Abstract]
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  26. "A phosphoglycerate kinase mutant (PGK Herlev; D285V) in a Danish patient with isolated chronic hemolytic anemia: mechanism of mutation and structure-function relationships."Hum. Mutat. 12:280-287(1998) [PubMed] [Europe PMC] [Abstract]
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