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Calbindin (CALB)

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CAB27; Calbindin 1,28kDa; Calbindin D28; Vitamin D-dependent calcium-binding protein, avian-type

Calbindin (CALB)
CCC G438
HGNC 1434
MGI 88248
PubMed 22544312
RGD 69340
UniProt P05937
Wiki Calbindin
Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted.
The sequence showed an open reading frame coding for a protein of 261 amino acids, containing 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The preliminary data suggested that the 29-kD protein in brain is encoded by a different gene.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG438Hu01 Recombinant Calbindin (CALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG438Hu01 Polyclonal Antibody to Calbindin (CALB) WB; IHC; ICC; IP.
MAG438Hu21 Monoclonal Antibody to Calbindin (CALB) WB; IHC; ICC; IP.
Assay Kits SEG438Hu ELISA Kit for Calbindin (CALB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG438Mu01 Recombinant Calbindin (CALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG438Mu01 Polyclonal Antibody to Calbindin (CALB) WB; IHC; ICC; IP.
Assay Kits SEG438Mu ELISA Kit for Calbindin (CALB) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPG438Ra01 Recombinant Calbindin (CALB) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAG438Ra01 Polyclonal Antibody to Calbindin (CALB) WB; IHC; ICC; IP.
LAG438Ra71 Biotin-Linked Polyclonal Antibody to Calbindin (CALB) WB; IHC; ICC.
MAG438Ra21 Monoclonal Antibody to Calbindin (CALB) WB; IHC; ICC; IP.
Assay Kits SEG438Ra ELISA Kit for Calbindin (CALB) Enzyme-linked immunosorbent assay for Antigen Detection.
  1. "Human 27-kDa calbindin complementary DNA sequence. Evolutionary and functional implications."Eur. J. Biochem. 170:207-215(1987) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "DNA sequence and analysis of human chromosome 8." Nature 439:331-335(2006) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The human calbindin 27-kDa gene: structural organization of the 5' and 3' regions, chromosomal assignment, and restriction fragment length polymorphism."Genomics 4:309-319(1989) [PubMed] [Europe PMC] [Abstract]
  6. "Calbindin D28K interacts with Ran-binding protein M: identification of interacting domains by NMR spectroscopy."Biochem. Biophys. Res. Commun. 303:1186-1192(2003) [PubMed] [Europe PMC] [Abstract]
  7. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]