Ethanolamine Kinase 1 (ETNK1)

[Edit]

EKI1; EKI

Ethanolamine Kinase 1 (ETNK1)
Ethanolamine kinase catalyzes the first step in phosphatidylethanolamine (PtdEtn) biosynthesis via the CDP-Etn pathway. The deduced 452-amino acid protein has a calculated molecular mass of 49.7 kD.
EKI1 contains a region rich in hydrophobic residues and a putative transmembrane helix. In transfected cells, however, EKI1 associated with the cytosolic fraction rather than the membrane fraction. Northern blot analysis detected a 2.2-kb EKI1 transcript in all tissues examined and an additional 1.7-kb EKI1 transcript in testis.EKI1 had negligible choline kinase activity in vitro, and overexpression did not influence phosphatidylcholine biosynthesis. Acceleration of the CDP-Etn pathway did not change the rate of PtdEtn formation via decarboxylation of phosphatidylserine

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Ethanolamine Kinase 1 (ETNK1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Ethanolamine Kinase 1 (ETNK1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Ethanolamine Kinase 1 (ETNK1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Ethanolamine Kinase 1 (ETNK1)CLIA Kit Customized Service Offer
n/aELISA Kit for Ethanolamine Kinase 1 (ETNK1)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Ethanolamine Kinase 1 (ETNK1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Ethanolamine Kinase 1 (ETNK1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Ethanolamine Kinase 1 (ETNK1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Ethanolamine Kinase 1 (ETNK1)CLIA Kit Customized Service Offer
n/aELISA Kit for Ethanolamine Kinase 1 (ETNK1)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Ethanolamine Kinase 1 (ETNK1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Ethanolamine Kinase 1 (ETNK1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Ethanolamine Kinase 1 (ETNK1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Ethanolamine Kinase 1 (ETNK1)CLIA Kit Customized Service Offer
n/aELISA Kit for Ethanolamine Kinase 1 (ETNK1)ELISA Kit Customized Service Offer
  1. "Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway."J. Biol. Chem. 276:2174-2179(2001) [PubMed] [Europe PMC] [Abstract]
  2. "The finished DNA sequence of human chromosome 12." Nature 440:346-351(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]