Malate Dehydrogenase 2 (MDH2)

[Edit]

M-MDH; MDH; MOR1; Malate Dehydrogenase 2,NAD(Mitochondrial)

Malate Dehydrogenase 2 (MDH2)
In both leukocytes and placentas, Davidson and Cortner (1967) found polymorphism of the malate dehydrogenase that is bound to mitochondria, called M-MDH originally and now symbolized MDH2. The fact that mitochondrial malate dehydrogenase was indistinguishable from normal in persons with variation in the supernatant MDH indicates that a separate locus is involved in its genetic determination. Mendelian segregation rather than maternal inheritance of MDH2 suggests that not all mitochondrial proteins are coded by mitochondrial DNA. Mitochondrial glutamic oxaloacetic transaminase is also determined by nuclear genes. From study of hybrid cells, Van Heyningen et al. (1975) mapped the locus for MDH2 to chromosome 7. Habets et al. (1992) subsequently mapped the locus to 7cen-q22.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPH672Hu01 Recombinant Malate Dehydrogenase 2 (MDH2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAH672Hu21 Monoclonal Antibody to Malate Dehydrogenase 2 (MDH2) WB; IHC; ICC; IP.
PAH672Hu01 Polyclonal Antibody to Malate Dehydrogenase 2 (MDH2) WB; IHC; ICC; IP.
Assay Kits SEH672Hu ELISA Kit for Malate Dehydrogenase 2 (MDH2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Malate Dehydrogenase 2 (MDH2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Malate Dehydrogenase 2 (MDH2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Malate Dehydrogenase 2 (MDH2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Malate Dehydrogenase 2 (MDH2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Malate Dehydrogenase 2 (MDH2) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Malate Dehydrogenase 2 (MDH2) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Malate Dehydrogenase 2 (MDH2) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Malate Dehydrogenase 2 (MDH2) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Malate Dehydrogenase 2 (MDH2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Malate Dehydrogenase 2 (MDH2) ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
  5. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
  6. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Regulation of cellular metabolism by protein lysine acetylation." Science 327:1000-1004(2010) [PubMed] [Europe PMC] [Abstract]
  8. "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
  9. "The first identification of lysine malonylation substrates and its regulatory enzyme."Mol. Cell. Proteomics 10:M111.012658.01-M111.012658.12(2011) [PubMed] [Europe PMC] [Abstract]
  10. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]
  11. "Crystal structure of human malate dehydrogenase type 2."Submitted (MAR-2006) to the PDB data bank