Dermal Microvascular Endothelial Cells (DMEC)

Vascular endothelial cells form the inner walls of blood vessels, high expression of adhesion molecules in inflammation, and blood flow in the white blood cell surface adhesion molecule interaction, so as to induce the white blood cells through the vascular wall.

Dermal vascular endothelial cells (DMEC) have common features with other vascular endothelial cells in the body,but they show some specific features of the skin. They actively participate in a variety of physiological processes, including wound healing, hemostasis, temperature regulation, regulation of inflammation/leukocyte transport.Signal transduction pathways control cell proliferation, quiescence, apoptosis and senescence, microvascular endothelial cells exhibit out significant phenotypic and functional heterogeneity, so as to make the skin capillaries in the dynamic balance between maintenance and remodeling.