Gastrulation Brain Homeobox Protein 1 (GBX1)

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Gastrulation and brain-specific homeobox protein 1

Gastrulation Brain Homeobox Protein 1 (GBX1)
The homeobox is a 180-bp DNA sequence that encodes a DNA-binding domain known as a homeodomain. To identify additional homeobox genes, Matsui et al. (1993) performed PCR using genomic DNA and degenerate primers based on conserved regions of the homeodomain. They isolated fragments of 2 novel homeobox genes, GBX1 and GBX2). The amino acid sequence of the predicted GBX1 and GBX2 homeodomains were identical. Sequence comparisons indicated that the GBX1/GBX2 homeodomain was most similar to that of chicken CHox-7. Northern blot analysis revealed that GBX1 was expressed as a 2.2-kb mRNA in 2 hematopoietic cell lines. Matsui et al. (1993) reported that the GBX1 gene is the human homolog of the mouse MMoxB, or Gbx1, gene identified by Murtha et al. (1991).

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Gastrulation Brain Homeobox Protein 1 (GBX1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Gastrulation Brain Homeobox Protein 1 (GBX1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Gastrulation Brain Homeobox Protein 1 (GBX1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Gastrulation Brain Homeobox Protein 1 (GBX1)CLIA Kit Customized Service Offer
n/aELISA Kit for Gastrulation Brain Homeobox Protein 1 (GBX1)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Gastrulation Brain Homeobox Protein 1 (GBX1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Gastrulation Brain Homeobox Protein 1 (GBX1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Gastrulation Brain Homeobox Protein 1 (GBX1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Gastrulation Brain Homeobox Protein 1 (GBX1)CLIA Kit Customized Service Offer
n/aELISA Kit for Gastrulation Brain Homeobox Protein 1 (GBX1)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Gastrulation Brain Homeobox Protein 1 (GBX1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Gastrulation Brain Homeobox Protein 1 (GBX1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Gastrulation Brain Homeobox Protein 1 (GBX1)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Gastrulation Brain Homeobox Protein 1 (GBX1)CLIA Kit Customized Service Offer
n/aELISA Kit for Gastrulation Brain Homeobox Protein 1 (GBX1)ELISA Kit Customized Service Offer
  1. "The DNA sequence of human chromosome 7." Nature 424:157-164(2003) [PubMed] [Europe PMC] [Abstract]
  2. "Expression of a novel human homeobox-containing gene that maps to chromosome 7q36.1 in hematopoietic cells."FEBS Lett. 322:181-185(1993) [PubMed] [Europe PMC] [Abstract]
  3. "NMR structure of the homeodomain transcription factor GBX1 from Homo sapiens."Submitted (JAN-2013) to the PDB data bank