Galactose-3-O-Sulfotransferase 1 (GAL3ST1)

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CST; Cerebroside Sulfotransferase; Galactosylceramide sulfotransferase; 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase

Galactose-3-O-Sulfotransferase 1 (GAL3ST1)
Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. GAL3ST1 is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma.
The GalCer sulfotransferase cDNA encodes a 423-amino acid protein with a predicted type II transmembrane topology and 2 potential N-linked glycosylation sites. GalCer sulfotransferase is not homologous to either the cytosolic sulfotransferases or the Golgi sulfotransferases.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ076Hu01 Recombinant Galactose-3-O-Sulfotransferase 1 (GAL3ST1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ076Hu01 Polyclonal Antibody to Galactose-3-O-Sulfotransferase 1 (GAL3ST1) WB; ICC; IHC-P; IHC-F; ELISA.
Assay Kits SEJ076Hu ELISA Kit for Galactose-3-O-Sulfotransferase 1 (GAL3ST1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Galactose-3-O-Sulfotransferase 1 (GAL3ST1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Galactose-3-O-Sulfotransferase 1 (GAL3ST1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Galactose-3-O-Sulfotransferase 1 (GAL3ST1) Polyclonal Antibody Customized Service Offer
Assay Kits SEJ076Mu ELISA Kit for Galactose-3-O-Sulfotransferase 1 (GAL3ST1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPJ076Ra01 Recombinant Galactose-3-O-Sulfotransferase 1 (GAL3ST1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAJ076Ra01 Polyclonal Antibody to Galactose-3-O-Sulfotransferase 1 (GAL3ST1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Galactose-3-O-Sulfotransferase 1 (GAL3ST1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Galactose-3-O-Sulfotransferase 1 (GAL3ST1) ELISA Kit Customized Service Offer
  1. "Molecular cloning and expression of cDNA encoding human 3'-phosphoadenylylsulfate:galactosylceramide 3'-sulfotransferase."J. Biol. Chem. 272:4864-4868(1997) [PubMed] [Europe PMC] [Abstract]
  2. "Cancer-associated alternative usage of multiple promoters of human GalCer sulfotransferase gene."Eur. J. Biochem. 267:2672-2679(2000) [PubMed] [Europe PMC] [Abstract]
  3. "A genome annotation-driven approach to cloning the human ORFeome."Genome Biol. 5:R84.1-R84.11(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Purification and characterization of 3'-phosphoadenosine-5'-phosphosulfate:GalCer sulfotransferase from human renal cancer cells."J. Biochem. 119:421-427(1996) [PubMed] [Europe PMC] [Abstract]