DNA Methyltransferase 1 (DNMT1)


CXXC9; DNMT; MCMT; Cytosine-5 DNA Methyltransferase 1; CXXC-type zinc finger protein 9; DNA methyltransferase HsaI

DNA Methyltransferase 1 (DNMT1)
DNA (cytosine-5)-methyltransferases (DNMTs), such as DNMT1, maintain patterns of methylated cytosine residues in the mammalian genome. Genomic methylation patterns are reshaped during gametogenesis and early development and undergo programmed alterations during cellular differentiation. Methylation patterns are responsible for the repression of parasitic sequence elements and the expression status of genes subject to genomic imprinting and X inactivation. Faithful maintenance of methylation patterns is required for normal mammalian development, and aberrant methylation patterns are associated with certain human tumors and developmental abnormalities.A DNMT1 enzyme is thought to be responsible for most of the maintenance as well as the de novo methylation activities occurring in the somatic cells of vertebrates.

Organism species: Homo sapiens (Human)

ProteinsRPJ244Hu01Recombinant DNA Methyltransferase 1 (DNMT1)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesPAJ244Hu01Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1)WB; IHC; ICC; IP.
MAJ244Hu21Monoclonal Antibody to DNA Methyltransferase 1 (DNMT1)WB; IHC; ICC; IP.
Assay KitsSEJ244HuELISA Kit for DNA Methyltransferase 1 (DNMT1)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

ProteinsRPJ244Mu01Recombinant DNA Methyltransferase 1 (DNMT1)Positive Control; Immunogen; SDS-PAGE; WB.
RPJ244Mu02Recombinant DNA Methyltransferase 1 (DNMT1)Positive Control; Immunogen; SDS-PAGE; WB.
AntibodiesPAJ244Mu01Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1)WB; IHC; ICC; IP.
PAJ244Mu02Polyclonal Antibody to DNA Methyltransferase 1 (DNMT1)WB; IHC; ICC; IP.
Assay KitsSEJ244MuELISA Kit for DNA Methyltransferase 1 (DNMT1)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

Proteinsn/aRecombinant DNA Methyltransferase 1 (DNMT1)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to DNA Methyltransferase 1 (DNMT1)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to DNA Methyltransferase 1 (DNMT1)Polyclonal Antibody Customized Service Offer
Assay KitsSEJ244RaELISA Kit for DNA Methyltransferase 1 (DNMT1)Enzyme-linked immunosorbent assay for Antigen Detection.
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