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Autophagy Related Protein 12 (ATG12)

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APG12; APG12L; HAPG12; Ubiquitin-like protein ATG12

Autophagy Related Protein 12 (ATG12)
CCC L224
HGNC 588
MGI 1914776
PubMed 23202584
RGD 1306306
UniProt O94817
Wiki ATG12
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy.
The C-terminal half of ATG12 shares significant similarity with yeast Apg12, including conservation of the C-terminal glycine, which is involved in Apg5 (ATG5)-Apg12 conjugation in yeast.ATG12 was conjugated to ATG5. Western blot analysis detected the ATG12-ATG5 conjugate at an apparent molecular mass of 65 kD. The C-terminal glycine of ATG12 was conjugated to a central lysine (lys130) of ATG5. Mutation of either residue abrogated conjugation.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Autophagy Related Protein 12 (ATG12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Autophagy Related Protein 12 (ATG12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Autophagy Related Protein 12 (ATG12) Polyclonal Antibody Customized Service Offer
Assay Kits SEL224Hu ELISA Kit for Autophagy Related Protein 12 (ATG12) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Autophagy Related Protein 12 (ATG12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Autophagy Related Protein 12 (ATG12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Autophagy Related Protein 12 (ATG12) Polyclonal Antibody Customized Service Offer
Assay Kits SEL224Mu ELISA Kit for Autophagy Related Protein 12 (ATG12) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Autophagy Related Protein 12 (ATG12) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Autophagy Related Protein 12 (ATG12) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Autophagy Related Protein 12 (ATG12) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Autophagy Related Protein 12 (ATG12) CLIA Kit Customized Service Offer
n/a ELISA Kit for Autophagy Related Protein 12 (ATG12) ELISA Kit Customized Service Offer
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