Prolactin Induced Protein (PIP)
[Edit]GCDFP15; GPIP4; BRST2; SABP; gp17; Gross cystic disease fluid protein 15; Prolactin-induced protein; Secretory actin-binding protein
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The hormonally responsive prolactin-inducible protein gene is expressed in benign and malignant breast tumor tissues and in some normal exocrine organs such as sweat, salivary, and lacrimal glands.The PIP gene is 7 kb long with 4 exons ranging from 106 bp to 223 bp.
PIP is overexpressed in 80% of primary and metastatic breast cancers, is duplicated in the breast carcinoma cell line T47D. The 2 copies are organized as a large palindrome, lying 'in loco' on one chromosome 7. The FRA7I fragile site lies 2 Mb telomeric to the PIP gene and sets the distal end of the repeated sequence. Breakage at the FRA7I site was repaired by 1 cycle of the breakage--fusion-bridge (BFB) cycle mechanism, resulting in amplification of the PIP gene.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPM035Hu01 | Recombinant Prolactin Induced Protein (PIP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAM035Hu01 | Polyclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC; IP. |
| MAM035Hu21 | Monoclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC; IP. | |
| Assay Kits | SEM035Hu | ELISA Kit for Prolactin Induced Protein (PIP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPM035Mu01 | Recombinant Prolactin Induced Protein (PIP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAM035Mu01 | Polyclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC; IP. |
| LAM035Mu81 | FITC-Linked Polyclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC; IF. | |
| LAM035Mu71 | Biotin-Linked Polyclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC. | |
| Assay Kits | n/a | CLIA Kit for Prolactin Induced Protein (PIP) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Prolactin Induced Protein (PIP) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPM035Ra01 | Recombinant Prolactin Induced Protein (PIP) | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPM035Ra02 | Recombinant Prolactin Induced Protein (PIP) | Positive Control; Immunogen; SDS-PAGE; WB. | |
| Antibodies | PAM035Ra01 | Polyclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC; IP. |
| LAM035Ra81 | FITC-Linked Polyclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC; IF. | |
| LAM035Ra71 | Biotin-Linked Polyclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC. | |
| MAM035Ra21 | Monoclonal Antibody to Prolactin Induced Protein (PIP) | WB; IHC; ICC; IP. | |
| PAM035Ra02 | Polyclonal Antibody to Prolactin Induced Protein (PIP) | WB,IHC | |
| Assay Kits | SEM035Ra | ELISA Kit for Prolactin Induced Protein (PIP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
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