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TEA Domain Family, Member 1 (TEAD1)

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REF1; AA; TCF13; TEF-1; NTEF-1; Transcription factor 13; Atrophia Areata,Peripapillary Chorioretinal Degeneration; SV40 Transcriptional Enhancer Factor

TEA Domain Family, Member 1 (TEAD1)
CCC M351
HGNC 11714
MGI 101876
PubMed 15016762
RGD 1549742
UniProt P28347
Wiki TEAD1
TEAD1 a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. This protein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptional repressor. Additional transcript variants have been described but their full-length natures have not been experimentally verified.
The enhancer of simian virus 40 (SV40) is a cis-acting regulatory element that stimulates transcription from RNA polymerase B(II) promoters. Genetic studies have demonstrated that this enhancer consists of multiple enhansons, GT-IIC, GT-I, TC-II, Sph-II, Sph-I, octamer, and P, which function synergistically in a cell-specific manner. In vitro binding studies have identified several proteins, some of which exhibit cell-specific activity, interacting with these SV40 enhansons.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPM351Hu02 Recombinant TEA Domain Family, Member 1 (TEAD1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAM351Hu02 Polyclonal Antibody to TEA Domain Family, Member 1 (TEAD1) WB; IHC; ICC; IP.
Assay Kits SEM351Hu ELISA Kit for TEA Domain Family, Member 1 (TEAD1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TEA Domain Family, Member 1 (TEAD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TEA Domain Family, Member 1 (TEAD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TEA Domain Family, Member 1 (TEAD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TEA Domain Family, Member 1 (TEAD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for TEA Domain Family, Member 1 (TEAD1) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant TEA Domain Family, Member 1 (TEAD1) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to TEA Domain Family, Member 1 (TEAD1) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to TEA Domain Family, Member 1 (TEAD1) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for TEA Domain Family, Member 1 (TEAD1) CLIA Kit Customized Service Offer
n/a ELISA Kit for TEA Domain Family, Member 1 (TEAD1) ELISA Kit Customized Service Offer
  1. "Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1."Cell 65:551-568(1991) [PubMed] [Europe PMC] [Abstract]
  2. "Human chromosome 11 DNA sequence and analysis including novel gene identification." Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "The TEA domain: a novel, highly conserved DNA-binding motif."Cell 66:11-12(1991) [PubMed] [Europe PMC] [Abstract]
  5. "TEAD mediates YAP-dependent gene induction and growth control."Genes Dev. 22:1962-1971(2008) [PubMed] [Europe PMC] [Abstract]
  6. "TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition."J. Biol. Chem. 284:13355-13362(2009) [PubMed] [Europe PMC] [Abstract]
  7. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
  8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
  9. "Insights into transcription enhancer factor 1 (TEF-1) activity from the solution structure of the TEA domain."Proc. Natl. Acad. Sci. U.S.A. 103:17225-17230(2006) [PubMed] [Europe PMC] [Abstract]
  10. "Structural insights into the YAP and TEAD complex."Genes Dev. 24:235-240(2010) [PubMed] [Europe PMC] [Abstract]
  11. "A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration)."Hum. Mol. Genet. 13:975-981(2004) [PubMed] [Europe PMC] [Abstract]