Intraflagellar Transport Protein 80 (IFT80)

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WDR56; WD Repeat Domain 56

Intraflagellar Transport Protein 80 (IFT80)
The IFT80 gene encodes a protein with 7 WD40 domains that is a component of the intraflagellar transport (IFT) complex B. The IFT is essential for the development and maintenance of motile and sensory cilia.
By sequencing clones obtained from a size-fractionated fetal brain cDNA library, Nagase et al. (2000) cloned IFT80, which they designated KIAA1374. The transcript contains repetitive elements in its 3-prime UTR, and the deduced protein contains 764 amino acids. RT-PCR ELISA detected moderate expression of IFT80 in adult brain, lung, liver, kidney, testis, and ovary, in all specific adult brain regions examined, and in fetal liver and brain. Little to no expression was detected in adult heart, skeletal muscle, pancreas, and spleen.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Intraflagellar Transport Protein 80 (IFT80)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Intraflagellar Transport Protein 80 (IFT80)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Intraflagellar Transport Protein 80 (IFT80)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Intraflagellar Transport Protein 80 (IFT80)CLIA Kit Customized Service Offer
n/aELISA Kit for Intraflagellar Transport Protein 80 (IFT80)ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Intraflagellar Transport Protein 80 (IFT80)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Intraflagellar Transport Protein 80 (IFT80)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Intraflagellar Transport Protein 80 (IFT80)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Intraflagellar Transport Protein 80 (IFT80)CLIA Kit Customized Service Offer
n/aELISA Kit for Intraflagellar Transport Protein 80 (IFT80)ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aRecombinant Intraflagellar Transport Protein 80 (IFT80)Recombinant Protein Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Intraflagellar Transport Protein 80 (IFT80)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Intraflagellar Transport Protein 80 (IFT80)Polyclonal Antibody Customized Service Offer
Assay Kitsn/aCLIA Kit for Intraflagellar Transport Protein 80 (IFT80)CLIA Kit Customized Service Offer
n/aELISA Kit for Intraflagellar Transport Protein 80 (IFT80)ELISA Kit Customized Service Offer
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence, annotation and analysis of human chromosome 3." Nature 440:1194-1198(2006) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro."DNA Res. 7:65-73(2000) [PubMed] [Europe PMC] [Abstract]
  5. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  6. "IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy."Nat. Genet. 39:727-729(2007) [PubMed] [Europe PMC] [Abstract]
  7. "Identification and characterization of a long isoform of human IFT80, IFT80-L."Biochem. Biophys. Res. Commun. 373:653-658(2008) [PubMed] [Europe PMC] [Abstract]