≡

Coiled Coil Domain Containing Protein 186 (CCDC186)

[Edit]

C10orf118; CTCL tumor antigen HD-CL-01/L14-2

Coiled Coil Domain Containing Protein 186 (CCDC186)
CCC R229
HGNC 24349
MGI 2445022
PubMed 12783626
UniProt Q7Z3E2
Wiki C10orf118
C10orf118 encoded by this open reading frame is the CTCL tumour antigen L14-2, a factor involved in processes of tumorigenesis. The surrounding regions of HH10 Helix I revealed a clear conservation of eight extra base pairs when compared with the HH9 region. Furthermore, the 50-ends of two expressed sequence tags were observed to match with this intronic region. Regarding the absence of the HH10 motif among some mammal species, a case of an inactive HHR motif was observed in the C10orf118 orthologue of the lagomorph Ochotona princeps, which suggests the loss of this HHR motif during the evolution of these mammals. Interestingly, a putative gene homologous to C10orf118 was detected in the S. mansoni genome. Inspection of the corresponding genomic sequence in the trematode revealed the presence of at least two HHR motifs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Coiled Coil Domain Containing Protein 186 (CCDC186) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Coiled Coil Domain Containing Protein 186 (CCDC186) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Coiled Coil Domain Containing Protein 186 (CCDC186) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Coiled Coil Domain Containing Protein 186 (CCDC186) CLIA Kit Customized Service Offer
n/a ELISA Kit for Coiled Coil Domain Containing Protein 186 (CCDC186) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Coiled Coil Domain Containing Protein 186 (CCDC186) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Coiled Coil Domain Containing Protein 186 (CCDC186) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Coiled Coil Domain Containing Protein 186 (CCDC186) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Coiled Coil Domain Containing Protein 186 (CCDC186) CLIA Kit Customized Service Offer
n/a ELISA Kit for Coiled Coil Domain Containing Protein 186 (CCDC186) ELISA Kit Customized Service Offer
  1. "The full-ORF clone resource of the German cDNA consortium."BMC Genomics 8:399-399(2007) [PubMed] [Europe PMC] [Abstract]
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  3. "SEREX identification of new tumour-associated antigens in cutaneous T-cell lymphoma."Br. J. Dermatol. 150:252-258(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Gene discovery in the hamster: a comparative genomics approach for gene annotation by sequencing of hamster testis cDNAs."BMC Genomics 4:22-22(2003) [PubMed] [Europe PMC] [Abstract]
  6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
  7. "An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome."J. Proteomics 96:253-262(2014) [PubMed] [Europe PMC] [Abstract]