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Chromosome 15 is one of the 23 pairs of chromosomes in humans. People normally have two copies of this chromosome. Chromosome 15 spans about 106 million base pairs (the building material of DNA) and represents between 3% and 3.5% of the total DNA in cells.
A type of blood cancer known as acute promyelocytic leukemia is caused by a rearrangement (translocation) of genetic material between chromosomes 15 and 17. This translocation, written as t(15;17), fuses part of the PML gene from chromosome 15 with part of the RARA gene from chromosome 17. This mutation is acquired during a person's lifetime and is present only in certain cells. This type of genetic change, called a somatic mutation, is not inherited.
A type of blood cancer known as acute promyelocytic leukemia is caused by a rearrangement (translocation) of genetic material between chromosomes 15 and 17. This translocation, written as t(15;17), fuses part of the PML gene from chromosome 15 with part of the RARA gene from chromosome 17. This mutation is acquired during a person's lifetime and is present only in certain cells. This type of genetic change, called a somatic mutation, is not inherited.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Arp2/3 Inhibition Protein (Arpin) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Arp2/3 Inhibition Protein (Arpin) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Arp2/3 Inhibition Protein (Arpin) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Arp2/3 Inhibition Protein (Arpin) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Arp2/3 Inhibition Protein (Arpin) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Arp2/3 Inhibition Protein (Arpin) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Arp2/3 Inhibition Protein (Arpin) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Arp2/3 Inhibition Protein (Arpin) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Arp2/3 Inhibition Protein (Arpin) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Arp2/3 Inhibition Protein (Arpin) | ELISA Kit Customized Service Offer |
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- "Analysis of the DNA sequence and duplication history of human chromosome 15." Nature 440:671-675(2006) [PubMed] [Europe PMC] [Abstract]
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
- "Initial characterization of the human central proteome."BMC Syst. Biol. 5:17-17(2011) [PubMed] [Europe PMC] [Abstract]
- "Inhibitory signalling to the Arp2/3 complex steers cell migration." Nature 503:281-284(2013) [PubMed] [Europe PMC] [Abstract]