Mouse Model for Myocardiosis

  • Product No.DSI505Mu03
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceMyocarditis induced by diphtheria toxin
  • Model Animal StrainsBalb/c Mice(SPF), healthy, male, age: 4~6weeks, body weight:18g~20g.
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group(low,medium,high).
  • Modeling Period4-6 weeks
  • Modeling MethodUse the inbred mice with weight of 18 ~ 20g, age 4 ~ 6 weeks. The mice were intraperitoneally inoculated with 0.2ml of Coxsackie B3m virus (CVB3m, Nancy strain) to establish the severe Viral Myocarditis (VMC) model. Extract tissue samples after 1 week of inoculation. ①.Observe activity, food intake, body weight, coat color, and survival rate etc. ②.Observe the size, texture, color of the heart, liver and spleen. Weigh heart, liver and spleen / body weight (%) and thymus/body weight (%), heart/liver(%), heart/spleen(%), liver/spleen(%). ③.Pathological examination, take a piece of myocardial tissue, fix with 10% formaldehyde, conventional HE staining, observe the myocardial pathological changes.
  • Applicationsn/a
  • Downloadn/a
  • UOM Each case
  • FOB US$  
    For more details, please contact local distributors!

Model Evaluation

Pathological Results

Cytokines Level

Statistical Analysis

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

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Catalog No. Related products for research use of Mus musculus (Mouse) Organism species Applications (RESEARCH USE ONLY!)
DSI505Mu01 Mouse Model for Myocardiosis n/a
DSI505Mu02 Mouse Model for Myocardiosis n/a
DSI505Mu03 Mouse Model for Myocardiosis n/a