Myocardial infarction(MI) is a term for anevent of heart attack. MI occurs when blood stops flowingproperly to a part of the heart, and the heart muscle isinjured because of lack of oxygen supply. And one of thecoronary arteries which supplies blood to the heart develops a blockage due to an unstable buildup of plaques, whiteblood cells, cholesterol and fat. If the event becomes serious then it is called as acute myocardialinfarction(AMI). Because adult cardiomyocyteshave little regenerative capacity, myocardial tissue lost in MIis replaced with fibrotic tissue, leading to cardiac dysfunction and Heart failure (HF).Recently, a number of papers have reported the research on cardiomyocyt......2023-03-31

On January 31, 2023, Yaoxing Chen, Neurobiology Laboratory, College of Veterinary Medicine, China Agricultural University, China, and his team published a paper titled “Gut microbiota-derived metabolites mediate theneuroprotective effect ofmelatonin incognitive impairment induced bysleep deprivation” in Microbiome. Their research showed that gut microbes and their metabolites mediate the ameliorative effects of melatonin on sleep deprivation-induced cognitive impairment.The kits [ELISA Kit for Tumor Necrosis Factor Alpha (TNFa), SEA133Mu; ELISA Kit for Interleukin 6 (IL6), SEA079Mu; ELISA Kit for Interleukin 4 (IL4), SEA077Mu; ELISA Kit for Interleukin 10 (IL10), SEA056Mu] of Cloud......2023-03-23

Lung cancer is the leading cause of cancer-related death worldwide, with non-small cell lung cancer (NSCLC) being the most common type (~85%). NSCLCs are subdivided into lung adenocarcinomas (LUADs;~50%), lung squamous cell carcinomas (LUSCs;~30%), and others (~20%). Although disease understanding, treatment options, and outcomes for lung cancer are improving, survival continues to be low.5-year survival in populations with lung cancer varies from 4-17% depending on stage and regional differences. Therefore, it is necessary to explore the underlying mechanisms of lung cancer development to support the design of new targeted therapeutic agents.1. KMT2D deficiency drives lung squamous ce......2023-03-22

On February 6, 2023, L. Tanner, Respiratory Medicine, Allergology, & Palliative Medicine, Department of Clinical Sciences Lund, Lund University and Skåne University Hospital, Sweden, and his team published a paper titled “Small-molecule-mediated OGG1 inhibition attenuates pulmonary inflammation and lung fibrosis in a murine lung fibrosis model” in Nature Communications. Their data suggest that the small molecule OGG1 inhibitor, TH5487, is a potentially clinically relevant treatment for idiopathic pulmonary fibrosis (IPF).The kits [ELISA Kit for Lactate Dehydrogenase (LDH), SEB864Mu] of Cloud-Clone brand was chosed in this article, we are so proud for supporting the reaserchers.Int......2023-03-15

On February 17, 2023,Yiguo Wang, State Key Laboratory of Membrane Biology, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, China, and his team published a paper titled “Famsin, a novel gut-secreted hormone, contributes to metabolic adaptations to fasting via binding to its receptor OLFR796” in Cell Research. Their results demonstrate that communication between the intestine and other organs by a famsin-OLFR796 signaling axis is critical for metabolic adaptations to fasting.The kits [High Sensitive ELISA Kit for Fibroblast Growth Factor 15 (FGF15), HEL154Mu] of Cloud-Clone brand was chosed in this article, we are so proud for supporting the re......2023-03-09

On December 23, 2022,Hoi Leong Xavier Wong, School of Chinese Medicine, Hong Kong Baptist University, China, and his team published a paper titled “Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2” in Nature Communications. Their findings provide in vivo evidence demonstrating the contribution of ACE2 shedding to the etiology of COVID-19.The kits [ELISA Kit for Angiotensin I Converting Enzyme 2 (ACE2), SEB886Mu, SEB886Hu; ELISA Kit for Matrix Metalloproteinase 14 (MMP14), SEC056Mu, SEC056Hu] of Cloud-Clone brand was chosed in this article, we are so proud for supporting the reaserchers.Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a glo......2023-02-28