Bone Morphogenetic Protein 2 (BMP2)

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BMP2A; BMP-2A; Hemochromatosis Modifier

Bone Morphogenetic Protein 2 (BMP2)

Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins. BMP-2 like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is involved also in cardiac cell differentiation and epithelial to mesenchymal transition. BMP-2 and BMP-7 are osteogenic BMPs: they have been demonstrated to potently induce osteoblast differentiation in a variety of cell types.

Bone morphogenetic protein 2 is shown to stimulate the production of bone and recombinant human protein (rhBMP-2) and is currently available for orthopaedic usage in the United States.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Hu01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling.
RPA013Hu02Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
APA013Hu01Active Bone Morphogenetic Protein 2 (BMP2)Cell culture; Activity Assays; In vivo assays.
AntibodiesPAA013Hu01Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
MAA013Hu22Monoclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
PAA013Hu02Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA013HuELISA Kit for Bone Morphogenetic Protein 2 (BMP2)Enzyme-linked immunosorbent assay for Antigen Detection
SCA013HuCLIA Kit for Bone Morphogenetic Protein 2 (BMP2)Chemiluminescent immunoassay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Mu01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
RPA013Mu02Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA013Mu01Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
LAA013Mu71Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)IHC;WB;ELISA
LAA013Mu81FITC-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)IHC;ICC;IF;WB
PAA013Mu02Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA013MuELISA Kit for Bone Morphogenetic Protein 2 (BMP2)Enzyme-linked immunosorbent assay for Antigen Detection
SCA013MuCLIA Kit for Bone Morphogenetic Protein 2 (BMP2)Chemiluminescent immunoassay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Ra01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA013Ra01Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
LAA013Ra71Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)IHC;WB;ELISA
MAA013Ra21Monoclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA013RaELISA Kit for Bone Morphogenetic Protein 2 (BMP2)Enzyme-linked immunosorbent assay for Antigen Detection
SCA013RaCLIA Kit for Bone Morphogenetic Protein 2 (BMP2)Chemiluminescent immunoassay for Antigen Detection

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Rb01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
RPA013Rb02Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA013Rb52Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
PAA013Rb51Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
LAA013Rb71Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)IHC;WB;ELISA
Assay KitsSEA013RbELISA Kit for Bone Morphogenetic Protein 2 (BMP2)Enzyme-linked immunosorbent assay for Antigen Detection
SCA013RbCLIA Kit for Bone Morphogenetic Protein 2 (BMP2)Chemiluminescent immunoassay for Antigen Detection

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Ca01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
RPA013Ca02Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA013Ca01Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
PAA013Ca02Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB; ICC; IHC-P; IHC-F; ELISA; IP; IF; FCM.
LAA013Ca71Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)IHC;WB;ELISA
Assay Kitsn/aCLIA Kit for Bone Morphogenetic Protein 2 (BMP2)CLIA Kit Customized Service Offer
n/aELISA Kit for Bone Morphogenetic Protein 2 (BMP2)ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Po01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
RPA013Po02Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA013Po01Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
PAA013Po02Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
LAA013Po71Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)IHC;WB;ELISA
Assay KitsSEA013PoELISA Kit for Bone Morphogenetic Protein 2 (BMP2)Enzyme-linked immunosorbent assay for Antigen Detection
SCA013PoCLIA Kit for Bone Morphogenetic Protein 2 (BMP2)Chemiluminescent immunoassay for Antigen Detection

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Bo01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
AntibodiesMAA013Bo21Monoclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
PAA013Bo01Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA013BoELISA Kit for Bone Morphogenetic Protein 2 (BMP2)Enzyme-linked immunosorbent assay for Antigen Detection

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Cp01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA013Cp01Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
Assay Kitsn/aCLIA Kit for Bone Morphogenetic Protein 2 (BMP2)CLIA Kit Customized Service Offer
n/aELISA Kit for Bone Morphogenetic Protein 2 (BMP2)ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA013Ga01Recombinant Bone Morphogenetic Protein 2 (BMP2)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA013Ga01Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
MAA013Ga21Monoclonal Antibody to Bone Morphogenetic Protein 2 (BMP2)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA013GaELISA Kit for Bone Morphogenetic Protein 2 (BMP2)Enzyme-linked immunosorbent assay for Antigen Detection
SCA013GaCLIA Kit for Bone Morphogenetic Protein 2 (BMP2)Chemiluminescent immunoassay for Antigen Detection
  1. "Novel regulators of bone formation: molecular clones and activities."Science 242:1528-1534(1988) [PubMed] [Europe PMC] [Abstract]
  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Direct isoform analysis of high-mannose-containing glycoproteins by on-line capillary electrophoresis electrospray mass spectrometry."Anal. Chem. 69:2510-2516(1997) [PubMed] [Europe PMC] [Abstract]
  4. "USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney."Biochem. Biophys. Res. Commun. 316:490-500(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment."Endocrinology 151:3909-3917(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution."J. Mol. Biol. 287:103-115(1999) [PubMed] [Europe PMC] [Abstract]