Bone Morphogenetic Protein 2 (BMP2)

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BMP2A; BMP-2A; Hemochromatosis Modifier

Bone Morphogenetic Protein 2 (BMP2)

Bone morphogenetic protein 2 or BMP-2 belongs to the TGF-β superfamily of proteins. BMP-2 like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. It is involved in the hedgehog pathway, TGF beta signaling pathway, and in cytokine-cytokine receptor interaction. It is involved also in cardiac cell differentiation and epithelial to mesenchymal transition. BMP-2 and BMP-7 are osteogenic BMPs: they have been demonstrated to potently induce osteoblast differentiation in a variety of cell types.

Bone morphogenetic protein 2 is shown to stimulate the production of bone and recombinant human protein (rhBMP-2) and is currently available for orthopaedic usage in the United States.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Hu01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA013Hu02 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
APA013Hu01 Active Bone Morphogenetic Protein 2 (BMP2) Cell culture; Activity Assays.
APA013Hu02 Active Bone Morphogenetic Protein 2 (BMP2) Cell culture; Activity Assays.
Antibodies PAA013Hu01 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
MAA013Hu22 Monoclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
PAA013Hu02 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
Assay Kits SEA013Hu ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA013Hu CLIA Kit for Bone Morphogenetic Protein 2 (BMP2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Mu01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA013Mu02 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA013Mu01 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
LAA013Mu71 Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC.
LAA013Mu81 FITC-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IF.
PAA013Mu02 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
Assay Kits SEA013Mu ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA013Mu CLIA Kit for Bone Morphogenetic Protein 2 (BMP2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Ra01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA013Ra01 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
LAA013Ra71 Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC.
MAA013Ra21 Monoclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
Assay Kits SEA013Ra ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA013Ra CLIA Kit for Bone Morphogenetic Protein 2 (BMP2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Oryctolagus cuniculus (Rabbit)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Rb01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA013Rb02 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA013Rb52 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
PAA013Rb51 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
LAA013Rb71 Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC.
Assay Kits SEA013Rb ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA013Rb CLIA Kit for Bone Morphogenetic Protein 2 (BMP2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Ca01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA013Ca02 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA013Ca01 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
PAA013Ca02 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
LAA013Ca71 Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC.
Assay Kits n/a CLIA Kit for Bone Morphogenetic Protein 2 (BMP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) ELISA Kit Customized Service Offer

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Po01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
RPA013Po02 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA013Po01 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
PAA013Po02 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
LAA013Po71 Biotin-Linked Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC.
Assay Kits SEA013Po ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA013Po CLIA Kit for Bone Morphogenetic Protein 2 (BMP2) Chemiluminescent immunoassay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Bo01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies MAA013Bo21 Monoclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
PAA013Bo01 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
Assay Kits SEA013Bo ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Cp01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA013Cp01 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Bone Morphogenetic Protein 2 (BMP2) CLIA Kit Customized Service Offer
n/a ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) ELISA Kit Customized Service Offer

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA013Ga01 Recombinant Bone Morphogenetic Protein 2 (BMP2) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA013Ga01 Polyclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
MAA013Ga21 Monoclonal Antibody to Bone Morphogenetic Protein 2 (BMP2) WB; IHC; ICC; IP.
Assay Kits SEA013Ga ELISA Kit for Bone Morphogenetic Protein 2 (BMP2) Enzyme-linked immunosorbent assay for Antigen Detection.
SCA013Ga CLIA Kit for Bone Morphogenetic Protein 2 (BMP2) Chemiluminescent immunoassay for Antigen Detection.
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  2. "The DNA sequence and comparative analysis of human chromosome 20." Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
  3. "Direct isoform analysis of high-mannose-containing glycoproteins by on-line capillary electrophoresis electrospray mass spectrometry."Anal. Chem. 69:2510-2516(1997) [PubMed] [Europe PMC] [Abstract]
  4. "USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney."Biochem. Biophys. Res. Commun. 316:490-500(2004) [PubMed] [Europe PMC] [Abstract]
  5. "Posttranslational activation of bone morphogenetic protein 2 is mediated by proprotein convertase 6 during decidualization for pregnancy establishment."Endocrinology 151:3909-3917(2010) [PubMed] [Europe PMC] [Abstract]
  6. "Crystal structure of human bone morphogenetic protein-2 at 2.7 A resolution."J. Mol. Biol. 287:103-115(1999) [PubMed] [Europe PMC] [Abstract]