Interleukin 13 (IL13)

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ALRH; BHR1; P600; IL-13; NC30

Interleukin 13 (IL13)

Interleukin 13 (IL-13) is produced primarily by activated T lymphocytes. It shows approximately 30% amino acid (aa) sequence identity with IL-4 and shares many biological properties with IL-4. IL-13 has multiple effects on the differentiation and functions of monocytes/macrophages. It can suppress the cytotoxic functions of monocytes/macrophages and the production of proinflammatory cytokines by monocytes/macrophages. The biological effects of IL-13 are mediated by specific high-affinity cell surface receptor complexes. The functional IL-13 receptor complex has been shown to consist of the low-affinity IL-13 receptor α chain and the IL-4 receptor α subunit (IL-4 Rα). This IL-13 receptor complex may also serve as an alternate high-affinity IL-4 receptor complex in IL-4 responsive cells that lack the γ chain.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Hu01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
APA060Hu01 Active Interleukin 13 (IL13) Cell culture; Activity Assays.
EPA060Hu61 Eukaryotic Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Hu01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
MAA060Hu22 Monoclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits SEA060Hu ELISA Kit for Interleukin 13 (IL13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Mu01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
RPA060Mu02 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Mu01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
PAA060Mu02 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits SEA060Mu ELISA Kit for Interleukin 13 (IL13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Ra01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
APA060Ra01 Active Interleukin 13 (IL13) Cell culture; Activity Assays.
Antibodies PAA060Ra01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
MAA060Ra21 Monoclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits SEA060Ra ELISA Kit for Interleukin 13 (IL13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rhesus monkey (Simian)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Si01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Si01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 13 (IL13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 13 (IL13) ELISA Kit Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Ca01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Ca01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
MAA060Ca21 Monoclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits SEA060Ca ELISA Kit for Interleukin 13 (IL13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Po01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Po01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
MAA060Po21 Monoclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits SEA060Po ELISA Kit for Interleukin 13 (IL13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Bo01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Bo01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
MAA060Bo21 Monoclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits SEA060Bo ELISA Kit for Interleukin 13 (IL13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Capra hircus; Caprine (Goat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Cp01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Cp01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Interleukin 13 (IL13) CLIA Kit Customized Service Offer
n/a ELISA Kit for Interleukin 13 (IL13) ELISA Kit Customized Service Offer

Organism species: Equus caballus; Equine (Horse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Eq01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Eq01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
MAA060Eq21 Monoclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits SEA060Eq ELISA Kit for Interleukin 13 (IL13) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Chicken (Gallus)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA060Ga01 Recombinant Interleukin 13 (IL13) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA060Ga01 Polyclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
MAA060Ga21 Monoclonal Antibody to Interleukin 13 (IL13) WB; IHC; ICC; IP.
Assay Kits SEA060Ga ELISA Kit for Interleukin 13 (IL13) Enzyme-linked immunosorbent assay for Antigen Detection.
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  9. "Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2."Structure 18:332-342(2010) [PubMed] [Europe PMC] [Abstract]
  10. "Genetic variants of IL-13 signalling and human asthma and atopy." Hum. Mol. Genet. 9:549-559(2000) [PubMed] [Europe PMC] [Abstract]
  11. "Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population."Am. J. Respir. Cell Mol. Biol. 25:377-384(2001) [PubMed] [Europe PMC] [Abstract]
  12. "A common IL-13 Arg130Gln single nucleotide polymorphism among Chinese atopy patients with allergic rhinitis."Hum. Genet. 113:387-390(2003) [PubMed] [Europe PMC] [Abstract]