Matrix Metalloproteinase 10 (MMP10)

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STMY2; SL2; Stromelysin 2; Transin-2

Matrix Metalloproteinase 10 (MMP10)

Chang et al. (2006) found that human umbilical vein endothelial cells in which HDAC7 (HDAC7A) expression was suppressed by RNA interference failed to adhere to each other. Microarray analysis showed that HDAC7 suppression led to dysregulation of numerous genes encoding extracellular matrix and adhesion proteins, including 6.5-fold upregulation of MMP10 and 8.6-fold downregulation of the MMP10 inhibitor, TIMP1.

Chang et al. (2006) found that HDAC7 downregulated MMP10 by associating with MEF2 , an MMP10 transcriptional activator. Hdac7 deletion in mice, which was embryonic lethal due to widespread vascular damage, resulted in dramatic upregulation of Mmp10 in the perivascular region and downregulation of Timp1 in endothelial cells.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA098Hu01Recombinant Matrix Metalloproteinase 10 (MMP10)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA098Hu01Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)WB, ICC, IHC-P, IHC-F, ELISA
MAA098Hu22Monoclonal Antibody to Matrix Metalloproteinase 10 (MMP10)WB, ICC, IHC-P, IHC-F, ELISA
LAA098Hu71Biotin-Linked Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)IHC;WB;ELISA
LAA098Hu81FITC-Linked Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)IHC;ICC;IF;WB
Assay KitsSEA098HuELISA Kit for Matrix Metalloproteinase 10 (MMP10)Enzyme-linked immunosorbent assay for Antigen Detection
SCA098HuCLIA Kit for Matrix Metalloproteinase 10 (MMP10)Chemiluminescent immunoassay for Antigen Detection

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA098Mu01Recombinant Matrix Metalloproteinase 10 (MMP10)SDS-PAGE; WB; ELISA; IP.
RPA098Mu02Recombinant Matrix Metalloproteinase 10 (MMP10)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA098Mu01Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)WB, ICC, IHC-P, IHC-F, ELISA
PAA098Mu02Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA098MuELISA Kit for Matrix Metalloproteinase 10 (MMP10)Enzyme-linked immunosorbent assay for Antigen Detection
SCA098MuCLIA Kit for Matrix Metalloproteinase 10 (MMP10)Chemiluminescent immunoassay for Antigen Detection

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA098Ra01Recombinant Matrix Metalloproteinase 10 (MMP10)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA098Ra01Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)WB, ICC, IHC-P, IHC-F, ELISA
MAA098Ra21Monoclonal Antibody to Matrix Metalloproteinase 10 (MMP10)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA098RaELISA Kit for Matrix Metalloproteinase 10 (MMP10)Enzyme-linked immunosorbent assay for Antigen Detection
SCA098RaCLIA Kit for Matrix Metalloproteinase 10 (MMP10)Chemiluminescent immunoassay for Antigen Detection

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
ProteinsRPA098Po01Recombinant Matrix Metalloproteinase 10 (MMP10)SDS-PAGE; WB; ELISA; IP.
AntibodiesPAA098Po01Polyclonal Antibody to Matrix Metalloproteinase 10 (MMP10)WB, ICC, IHC-P, IHC-F, ELISA
MAA098Po21Monoclonal Antibody to Matrix Metalloproteinase 10 (MMP10)WB, ICC, IHC-P, IHC-F, ELISA
Assay KitsSEA098PoELISA Kit for Matrix Metalloproteinase 10 (MMP10)Enzyme-linked immunosorbent assay for Antigen Detection
SCA098PoCLIA Kit for Matrix Metalloproteinase 10 (MMP10)Chemiluminescent immunoassay for Antigen Detection
  1. "The collagenase gene family in humans consists of at least four members."Biochem. J. 253:187-192(1988) [PubMed] [Europe PMC] [Abstract]
  2. "Complete sequencing and characterization of 21,243 full-length human cDNAs." Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
  4. "Crystal structure of the catalytic domain of human matrix metalloproteinase 10."J. Mol. Biol. 336:707-716(2004) [PubMed] [Europe PMC] [Abstract]
  5. "The consensus coding sequences of human breast and colorectal cancers." Science 314:268-274(2006) [PubMed] [Europe PMC] [Abstract]