Collagen Type III (COL3)

Type III collagen is a fibrillar forming collagen comprising three alpha1(III) chains and is expressed in early embryos and throughout embryogenesis. In the adult, type III collagen is a major component of the extracellular matrix in a variety of internal organs and skin. Mutations in the COL3A1 gene have been implicated as a cause of type IV Ehlers-Danlos syndrome, a disease leading to aortic rupture in early adult life.  The mutated allele was transmitted through the mouse germ line and homozygous mutant animals were derived from heterozygous intercrosses. About 10% of the homozygous mutant animals survived to adulthood but have a much shorter life span compared with wild-type mice. The major cause of death of mutant mice was rupture of the major blood vessels, similar to patients with type IV Ehlers-Danlos syndrome. Type III collagen is essential for normal collagen I fibrillogenesis in the cardiovascular system and other organs.

Organism species: Homo sapiens (Human)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aComplete Antigen of Collagen Type III (COL3)Antigenic Transformation Customized Service Offer
AntibodiesPAA176Hu01Polyclonal Antibody to Collagen Type III (COL3)WB; IHC; ICC; IP.
LAA176Hu71Biotin-Linked Polyclonal Antibody to Collagen Type III (COL3)WB; IHC; ICC.
Assay KitsSEA176HuELISA Kit for Collagen Type III (COL3)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aComplete Antigen of Collagen Type III (COL3)Antigenic Transformation Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Collagen Type III (COL3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Collagen Type III (COL3)Polyclonal Antibody Customized Service Offer
Assay KitsSEA176MuELISA Kit for Collagen Type III (COL3)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aComplete Antigen of Collagen Type III (COL3)Antigenic Transformation Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Collagen Type III (COL3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Collagen Type III (COL3)Polyclonal Antibody Customized Service Offer
Assay KitsSEA176RaELISA Kit for Collagen Type III (COL3)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aComplete Antigen of Collagen Type III (COL3)Antigenic Transformation Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Collagen Type III (COL3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Collagen Type III (COL3)Polyclonal Antibody Customized Service Offer
Assay KitsSEA176PoELISA Kit for Collagen Type III (COL3)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aComplete Antigen of Collagen Type III (COL3)Antigenic Transformation Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Collagen Type III (COL3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Collagen Type III (COL3)Polyclonal Antibody Customized Service Offer
Assay KitsSEA176BoELISA Kit for Collagen Type III (COL3)Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Equus caballus; Equine (Horse)

CATALOG NO.PRODUCT NAMEAPPLICATIONS
Proteinsn/aComplete Antigen of Collagen Type III (COL3)Antigenic Transformation Customized Service Offer
Antibodiesn/aMonoclonal Antibody to Collagen Type III (COL3)Monoclonal Antibody Customized Service Offer
n/aPolyclonal Antibody to Collagen Type III (COL3)Polyclonal Antibody Customized Service Offer
Assay KitsCEA176EqELISA Kit for Collagen Type III (COL3)Enzyme-linked immunosorbent assay for Antigen Detection.