Heme Oxygenase 1 (HO1)

Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, O2 and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; “free” iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5’- or 3’- UTRs of the mRNAs.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA584Hu01 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA584Hu02 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA584Hu01 Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
MAA584Hu22 Monoclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
LAA584Hu71 Biotin-Linked Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC.
LAA584Hu81 FITC-Linked Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IF.
MAA584Hu21 Monoclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
Assay Kits SEA584Hu ELISA Kit for Heme Oxygenase 1 (HO1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA584Mu01 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA584Mu02 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA584Mu01 Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
LAA584Mu71 Biotin-Linked Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC.
PAA584Mu02 Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
Assay Kits SEA584Mu ELISA Kit for Heme Oxygenase 1 (HO1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA584Ra01 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA584Ra02 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA584Ra01 Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
LAA584Ra71 Biotin-Linked Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC.
LAA584Ra81 FITC-Linked Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IF.
MAA584Ra21 Monoclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
Assay Kits SEA584Ra ELISA Kit for Heme Oxygenase 1 (HO1) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Sus scrofa; Porcine (Pig)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA584Po01 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
RPA584Po02 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA584Po01 Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
LAA584Po81 FITC-Linked Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IF.
LAA584Po71 Biotin-Linked Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC.
PAA584Po02 Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Heme Oxygenase 1 (HO1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heme Oxygenase 1 (HO1) ELISA Kit Customized Service Offer

Organism species: Bos taurus; Bovine (Cattle)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA584Bo01 Recombinant Heme Oxygenase 1 (HO1) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA584Bo01 Polyclonal Antibody to Heme Oxygenase 1 (HO1) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Heme Oxygenase 1 (HO1) CLIA Kit Customized Service Offer
n/a ELISA Kit for Heme Oxygenase 1 (HO1) ELISA Kit Customized Service Offer
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