Advanced Glycation End Product (AGE)

Advanced Glycation End products (AGEs) are the result of a chain of chemical reactions after an initial glycation reaction. The intermediate products are known, variously, as Amadori, Schiff base and Maillard products, named after the researchers who first described them. Side products generated in intermediate steps may be oxidizing agents or not. "Glycosylation" is sometimes used for "glycation" in the literature, usually as 'non-enzymatic glycosylation.' AGEs may be formed external to the body (exogenously) by heating (e.g., cooking) sugars with fats or proteins; or inside the body (endogenously) through normal metabolism and aging. Under certain pathologic conditions (e.g., oxidative stress due to hyperglycemia in patients with diabetes), AGE formation can be increased beyond normal levels. AGEs are now known to play a role as proinflammatory mediators in gestational diabetes as well.

Organism species: Pan-species (General)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins NPB353Ge01 Native Advanced Glycation End Product (AGE) Positive Control; Immunogen; SDS-PAGE; WB.
APB353Ge01 Active Advanced Glycation End Product (AGE) Cell culture; Activity Assays.
Antibodies PAB353Ge01 Polyclonal Antibody to Advanced Glycation End Product (AGE) WB; IHC; ICC; IP.
LAB353Ge71 Biotin-Linked Polyclonal Antibody to Advanced Glycation End Product (AGE) WB; IHC; ICC.
LAB353Ge81 FITC-Linked Polyclonal Antibody to Advanced Glycation End Product (AGE) WB; IHC; ICC; IF.
MAB353Ge21 Monoclonal Antibody to Advanced Glycation End Product (AGE) WB; IHC; ICC; IP.
Assay Kits CEB353Ge ELISA Kit for Advanced Glycation End Product (AGE) Enzyme-linked immunosorbent assay for Antigen Detection.
HEB353Ge High Sensitive ELISA Kit for Advanced Glycation End Product (AGE) Enzyme-linked immunosorbent assay for Antigen Detection.